SUMMARY The caudal neurosecretory system (CNSS) of the euryhaline flounder is involved in osmoregulatory responses underlying adaptation to seawater and freshwater. This study compared electrophysiological activity and responses to cholinergic agonists in the neuroendocrine Dahlgren cells in an in vitro preparation taken from fully seawater- (SWA) or freshwater-adapted(FWA) fish. Resting membrane and action potential parameters showed few differences between SWA and FWA cells. The hyperpolarisation-activated sag potential and depolarising afterpotential were present under both conditions;however, amplitude of the latter was significantly greater in SWA cells. The proportions of cells within the population exhibiting different firing patterns were similar in both adaptation states. However, bursting parameters were more variable in FWA cells, suggesting that bursting activity was less robust. The muscarinic agonist, oxotremorine, was largely inhibitory in Dahlgren cells, but increased activity in a non-Dahlgren cell population,α neurons. Nicotine promoted bursting activity in SWA Dahlgren cells,whereas it inhibited over half of FWA cells.

Research collections are an important tool for understanding the Earth, its systems, and human interaction. Despite the importance of collections, many are not maintained or curated as thoroughly as we would like. Part of the reason for this is the lack of professional reward for collection, curation, or maintenance. To address this gap in attribution metadata, the Research Data Alliance (RDA) and the Biodiversity Information Standards (TDWG) organization co-endorsed a Working Group to create recommendations for the representation of attribution metadata. After 18 months, this Working Group recommended the use of PROV entities and properties to link people (Agent), the curatorial actions they perform (Activity), and the digital or physical objects they are curating (Entity). Assigning a Role to an Agent is optional. These recommendations are discussed in the context of the RDA, TDWG, and existing standards. Future work includes adapting these recommendations to the specific needs of TDWG and developing a pilot application in collaboration with ORCID and the Data Futures project.

The Natural History Museum, London (NHM), generates and holds some of the largest global data sets relating to the biological and geological diversity of the natural world. A majority of these data were, until 2015, not widely accessible, and, even when published, were typically hard to find, poorly documented and in formats that impede discovery and integration. To better serve the bespoke needs of user communities outside and within the NHM, a dedicated data portal was developed to surface these data sets and provide a sustainable platform to encourage their citation and reuse. This paper describes the technical development of the data portal, from its inception to beta launch in December 2015, its first 2 years of operation, and future plans for the project. It outlines the development principles adopted for this prototypical project, which subsequently informed new digital project management methodologies at the NHM. The process of developing the data portal acted as a driver to implement policies necessary to encourage a culture of data sharing at the NHM.

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Natural Science Collections (NSCs) contain specimen-related data from which we extract valuable information for science and policy. Openness of those collections facilitates development of science. Moreover, virtual accessibility to physical containers by means of their digitization will allow an exponential increase in the level of available information. Digitization of collections will allow us to set a comprehensive registry of reliable, accurate, updated, comparable and interconnected information. Equally, the scope of interested potential users will largely expand and so will the different levels of granularity required by researchers, institutions and governmental bodies. Meeting diverse needs entails a special effort in data management and data analysis to extract, digest and present information on a compressed but still precise and objective-oriented format. The Collections Digitisation Dashboard (CDD) underpins such an attempt. The CDD stands as a practical tool that specifically aims to support high-level decisions with a wide coverage of data, by providing a visual, simplified and structured arrangement that will allow discovery of key indicators concerning digitization of bio- and geodiversity collections. The realm of possible approaches to the CDD covers levels of digitization, collection exceptionality, resourceavailability and many others. Still all those different angles need to be aligned and processed at once to provide an overall overview of the status of NSCs in the digitization process and analyse its further development. The CDD is a powerful mechanism to identify priorities, specialisation lines together with regional development, gaps and niches and future capabilities as well, and strengths and weaknesses across collections, institutions, countries and regions. It can perfectly underpin measurable and comparable assessments, with evolution indexes and progress indicators, all under an overarching homogenous approach. The Distributed System of Scientific Collections (DiSSCo) Research Infrastructure, currently in its preparatory phase, is built on top of the largest ever community of collections-related institutions across Europe and anchored on the Consortium of European Taxonomic Facilities (CETAF). It aims to provide a unique virtual access point to NSCs by facilitating a large and massive digitisation effort throughout Europe. Setting up priorities and specialization areas is pivotal to its success. To that end, the DiSSCo CDD will provide a valuation tool to summarize and showcase NSC's digitization status on a first-hand visualization. Different projects and initiatives will contribute, jointly and on a synergetic basis, to the production of the DiSSCo CDD. The ICEDIG project will address its basics features, terms of classification and tiers of information, and will produce a prototype and a set of recommendations on how to better attempt a massive dashboard by collating specific collections-based information and defining global strategic representations. CETAF working groups on collections and digitization will provide the desired homogeneity in describing and capturing the different implementation requirements from the users’ perspectives, which will be complemented by the contributions made under the umbrella of the COST Action MOBILISE. The Action will use networking activities to identify the right standards and policies to enable enlarging the scope of the DiSSCo CDD and its broader implementation by linking to the TDWG criteria and adopted standards. Complementarily, the ELViS platform to be developed under the SYNTHESYS+ project will provide the right virtual environment. Furthermore, SYNTHESYS+ will address the assessment capabilities of the CDD to enable the visual representation becoming a practical assessment mechanism and endow it with a dynamic feature for analysis over the time. The DiSSCo CDD will thus become an instrumental mechanism for decision-taking that will be embedded into the clustering initiative of products and services provided to the EOSCby the ENVRI-FAIR project in the environmental domain.