A 3-year-old, 29.5 kg female, spayed, labrador retriever cross with a 5-month history of severe, persistent papillomas affecting the oral mucous membranes was successfully treated using a multimodal approach that included staged aggressive cryotherapy. On presentation, verrucous growths varying in sizes of 2 mm–3 cm were appreciated affecting all tissues of the oral cavity. There were two alopecic, pedunculated growths with frond-like projections approximately 4 mm by 4 mm and 1 cm by 4 mm on the left pelvic paw. While the growths on the paws resolved with minimal intervention, the oral verrucous growths remained. A combination of interferon alpha-2B, canine papillomavirus-1 autologous vaccine, surgical excision, carbon dioxide laser ablation and aggressive cryotherapy led to complete resolution and continued remission of the canine oral viral papillomas.

A 12-year-old neutered male Siberian husky dog was evaluated for alopecia, pyoderma, and diarrhoea suspected to be associated with a functional thyroid carcinoma. Treatment which included a thyroidectomy and subsequent thyroid supplementation led to the resolution of all associated clinical signs. There has been no recurrence of alopecia, pyoderma, or gastrointestinal abnormalities after one year of thyroid supplementation and post thyroidectomy. To the best of the authors' knowledge, this is the first report of a functional thyroid tumour in a dog associated with hair coat, skin, and gastrointestinal abnormalities.