Context: Candidal vulvovaginitis causes discomfort and increased HIV infectivity because viral shedding is increased among these women. Aim: To determine the prevalence of Candida infections among HIV seropositive women in the special treatment (STC) and the gynecological clinics of Barau Dikko Teaching Hospital and the antifungal susceptibility patterns of the isolates. Study Design: We conducted a cross-sectional study among HIV-positive women accessing care in our hospital. Methods and Materials: A total of 312 high vaginal swabs (HVS) were collected from HIV seropositive women with clinical features of vulvovaginitis between February and July 2019. Wet mount preparations in potassium hydroxide (KOH) and Gram stained smears were performed directly on specimens. Cultures for Candida species were performed using Sabouraud dextrose agar (SDA) (Oxoid, UK) at room temperature (28°C) and in the incubator at 37 °C. Antifungal susceptibility of the Candida species to amphotericin B, clotrimazole, fluconazole, and miconazole was assessed using the ATB FUNGUS 4 test kits (bioMerieux, Marcy l'Etoile, France). Statistical Analysis Used: Data collected were analyzed using SPSS, Version 23. Results: Out of the 312 HVS cultured, 40 yielded Candida species giving a point prevalence of 12.8% in the study population. Candida species isolated from HVS specimens were Candida tropicalis (n = 14, 4.5%), Candida glabrata (n = 13, 4.2%), Candida krusei (n = 11, 3.5%), Candida dubliniensis (n = 1, 0.3%), and others C. glabrata/C. tropicalis (n = 1, 0.3%). Susceptibility of the isolates to antifungal agents ranged from 27.5% to 52.5%. Amphotericin B was the best performing antifungal agent with a sensitivity of 52.5%. Conclusion: The prevalence from our study was low compared to other studies among HIV seropositive women.
Acquired Gynaetresia is underreported in developing countries and is usually due to harmful cultural practices. It may result from obstructed labor or labor trauma. This is a rare case report of a 26-year-old P1 + 0 who presented with no penetration during coitus and history of amenorrhea about 1 year and 7 months after cesarean delivery. Failed attempts at vacuum extraction were made before surgery. She was investigated and a diagnosis of Gynaetresia with cryptomenorrhea was confirmed. She had vaginoplasty and menstrual and sexual functions were established. Postpartum genital examination should be ensured, no matter the mode of delivery to ensure Gynaetresia is diagnosed early and managed promptly.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.