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A dual-analyte optical chemical sensor platform based on the surface patterning of fluorescent dyes immobilized in sol-gel thin films is demonstrated as a proof of principle for a potential multi-analyte detection system with implications for lab-on-a-chip technology. A combination of hot embossing and an eccentric spin-coating technique was used to achieve discrete deposition of oxygen and carbon dioxide sensitive zones on a single waveguiding platform. Imaging of fluorescence from the oxygen and carbon dioxide sensing areas was performed using a low-cost CCD camera and fluorescence quenching on analyte exposure was characterized.

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Abstract. In this paper the theoretical base and experimental results of a new class of fiber optical supported surface plasmon resonance spectroscopy (SPRS) transducer is given. Surface plasmons were excited by polychromatic light, and the resonant excitation is detected as an intensity minimum in the measured spectra at certain wavelengths. The excitation takes place at the end zone of a multimode fiber coated with a thin surface plasmon resonance supporting metal layer. As examples for the large application field of this transducer a fiber optical immunosensor for the detection of antibodies against bovine serum albumin and a gas sensor for remote detection of tetrachloroethene was constructed and tested successfully. The sensors were constructed following the theoretical predictions for an optimal performance.

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