From the available evidence there is no need to advise any restriction on tea drinking in healthy people with no risk of iron deficiency. In groups at risk of iron deficiency the advice should be to drink tea between meals and to wait at least 1 h after eating before drinking tea.
. M i r t e s V. Beirao. Univ. o f Pa. Sch. o f Med., Pa. Hosp, Dept. Pediat. P h i l a . No evidence o f phototherapy r e l a t e d deficiency has y e t been found i n these 5 years. S i m i l a r l y there has been no evidence o f t r e a tment r e l a t e d decrease i n G6PD a c t i v i t y o r GSH blood content. H wever low GSH l e v e l s a r e not infrequently found i n small sick babies regardless o f Rx. Beginning studies o f a second FAD dependendent enzyme, methemoglobin reductase(MR) a r e showing s i m i l a r r es u l t s , except t h a t MR a c t i v i t y i n contrast t o t h a t o f GR i s lower i n newborn RBC than i n adult. Occasional instances o f s l i g h t l y l ower a c t i v i t y following onset o f Rx have a l l reversed themselves before cessation of Rx. These data differ from those of Gromiscl~ e t . a l . perhaps because o f differences i n maternal n u t r i t i o n . --*APA-um p-nitrophenol phosphatelgm proteinlmin +P<0.005. Conclusion: 80% of pta with GSE exhibited in vitro gluten sensitivity while gluten had no effect on non-GSE flat jejunal mucosa. In vitro gluten sensitivity appears to be specific for the diagnosis of GSE, thus perhaps obviating repeat biopsies and challenge to confirm the diagnosis in these pts. Ulceration recurred within 10 daya after drug discontinuation necessitating its resumption and ongoing use. m j o r hemorrhage from atrusa ulcers (a teroid-induced, bilisry atrerialport-Usei operation) in the other two children ceaeed within 24 hour* aftinstitution of cirtidine. Serial gastric acid etudias in the a u l l e r children s h a n d inconatant control of gastric secretion probably d w to lack of exprience with dosaga. Naverthelesa. there was prompt radiographic healing of duodenal ulcara tion in both patients. Drug toxicity waa monitorad by mequential heutologic, renal, hepatic and neurologic mtudias. Although most likely not drug-related. a tranaimnt decreaae in bile output in one patient and lethargy in another repranentad the only poerible toxic ride effects obaervad thue far.
For the past 5 years we have been doing s e r i a l deterininations o f the a c t i v i t y o f the f l avin adenine dinucleotide(FA0) dependent enzyme, glutathione reductase (GR) i n RBC's of babies undergoing phototherapy. A c t i v i t y . f o l l o w i n q i n v i t r o exposure totFAD,is a l s o measured(method o f Glatzle
RELATION OF SPECIFIC DYNAMIC ACTION (SDA) TO
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