Since their discovery in the monkey and human brain, mirror neurons have been claimed to play a key role in understanding others' intentions. For example, "action-constrained" mirror neurons in inferior parietal lobule fire when the monkey observes a grasping movement that is followed by an eating action, but not when it is followed by a placing action. It is claimed these responses enable the monkey to predict the intentions of the actor. These findings have been replicated in human observers by recording electromyography responses of the mouth-opening mylohyoid muscle during action observation. Mylohyoid muscle activity was greater during the observation of actions performed with the intention to eat than of actions performed with the intention to place, again suggesting an ability to predict the actor's intentions. However, in previous studies, intention was confounded with object type (food for eating actions, nonfood for placing actions). We therefore used electromyography to measure mylohyoid activity in participants observing eating and placing actions. Unlike previous studies, we used a design in which each object (food, nonfood) could be both eaten and placed, and thus participants could not predict the actor's intention at the onset of the action. Greater mylohyoid activity was found for the observation of actions performed on food objects, irrespective of intention, indicating that the object type, not the actor's intention, drives the mirror response. This result suggests that observers' motor responses during action observation reflect the presence of a particular object, rather than the actor's underlying intentions.

Introduction: There is increasing evidence that major depressive disorder (MDD) is associated with significant pragmatic language impairments. However, there is a lack of studies that use standardized tools and simultaneously investigate all pragmatic language skills among MDD patients. The aim of this study was to propose a more thorough investigation of all pragmatic language skills in patients with MDD. Methods: Twenty adults (aged 22–65) with a DSM-5 diagnosis of MDD were assessed using BLED Santa Lucia (Batteria sul Linguaggio dell’Emisfero Destro Santa Lucia), a battery designed to evaluate pragmatic language skills (comprehension of inferences, of picture and written metaphors, of indirect requests, of humoristic expressions, and of prosody). The performance of the MDD participants on all BLED Santa Lucia subscales was compared to 20 healthy control subjects (aged 20–60) matched for gender, age, years of education, and employment status. Results: MDD patients performed poorer than controls in comprehension of inferences (p < 0.01), picture metaphors (p < 0.001), written metaphors (p < 0.001), indirect requests (p < 0.01), humoristic expression (p < 0.05), and prosody (p < 0.05). Conclusions: All pragmatic language skills can be significantly impaired in MDD patients. A valid assessment of all pragmatic language skills can allow, for each patient, the definition of a specific profile of risk and protective factors before and during psychotherapy.

Nel presente contributo gli Autori propongono alcune riflessioni sulla natura musicale della psicoterapia, coerentemente con un modello estetico della clinica relazionale con l'individuo, la coppia e la famiglia. Tale modello mette in evidenza la ricchezza delle qualita ritmiche e musicali della relazione intersoggettiva, accostando lo sviluppo del processo terapeutico alle caratteristiche della musica jazz e al rapporto tra esecuzione e improvvisazione. Una serie di dialoghi tra "un padre e una figlia", ispirati ai celebri metaloghi di batesoniana memoria, arricchiscono i contenuti del testo.

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