These results demonstrate that clinical lupine allergy is very uncommon, even in the presence of sensitization to lupine flour. The estimated prevalence of lupine allergy, among patients with a suspected food allergy, referred to a tertiary allergy centre in the Netherlands is 0.27-0.81%. In most, although not all cases, sensitization is not clinically relevant and is most likely caused by cross-sensitization to peanut. In selected cases, eliciting doses are low, making significant reactions possible.

are principals of Red Maple Trials. J.M. and N.S. are employees of Red Maple Trials. D.B. is the veterinarian-owner of the Merivale Cat Hospital; he was reimbursed for his work in the study.

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