Fever is a condition when the body temperature increases to more than 380C. Fever indicates the presence of a disease or other condition in the body. Fever generally occurs as a reaction of the immune system to fight viral, bacterial, fungal, or parasitic infections that cause disease. Some of the diseases that often cause fever are flu, sore throat, and urinary tract infections. Fever can happen to anyone, starting frombaby, children, to adults. This disease can be cured by using drugs that contain antipyretics, analgesics and anti-inflammatory. Jatropha leaves contain active compounds in the form of flavonoids which contain antipyretics, analgesics, and anti-inflammatory properties. Here will be explained about the content of jatropha leaves which can be used as a medicine for fever.