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Abstract. Discussed in this paper are the issues underlying the mechanical design of a seven-axes isotropic manipulator. The kinematic design of this manipulator was made based on one main criterion, namely, accuracy. Thus, the main issue determining the underlying architecture, defined by its Hartenberg-Denavit (HD) parameters, was the optimization of its kinematic conditioning. This main criterion led not to one set of HD parameters, but rather to a manifold of these sets, which allowed the incorporation of further requirements, such as structural behavior, workspace considerations and functionality properties. These requirements in turn allowed the determination of the link shapes and the selection of actuators. The detailed mechanical design led to heuristic rules that helped in the decision-making process in defining issues such as link sub-assemblies and motor location along the joint axes.

Primary tumors of patients can release circulating tumor cells (CTCs) to flow inside of their blood. The CTCs have different mechanical properties in comparison with red and white blood cells, and their detection may be employed to study the efficiency of medical treatments against cancer. We present the design of a novel MEMS microgripper with rotatory electrostatic comb-drive actuators for mechanical properties characterization of cells. The microgripper has a compact structural configuration of four polysilicon layers and a simple performance that control the opening and closing displacements of the microgripper tips. The microgripper has a mobile arm, a fixed arm, two different actuators and two serpentine springs, which are designed based on the SUMMiT V surface micromachining process from Sandia National Laboratories. The proposed microgripper operates at its first rotational resonant frequency and its mobile arm has a controlled displacement of 40 µm at both opening and closing directions using dc and ac bias voltages. Analytical models are developed to predict the stiffness, damping forces and first torsional resonant frequency of the microgripper. In addition, finite element method (FEM) models are obtained to estimate the mechanical behavior of the microgripper. The results of the analytical models agree very well respect to FEM simulations. The microgripper has a first rotational resonant frequency of 463.8 Hz without gripped cell and it can operate up to with maximum dc and ac voltages of 23.4 V and 129.2 V, respectively. Based on the results of the analytical and FEM models about the performance of the proposed microgripper, it could be used as a dispositive for mechanical properties characterization of circulating tumor cells (CTCs).

The solid modeling of bevel gears has been recognized as a major design challenge. Various approaches have been proposed to approximate the theoretical involute-generated contact surface of bevel gears. As a means to accurately represent contact surfaces of these gears, the exact spherical involute is introduced here. The solid models of straight and spiral bevel gears are obtained by applying simple sweeping techniques to their tooth profiles, which are described by the exact spherical involute. Futhermore, the volumetric properties of the modeled bevel gears are readily computed from their piecewise-linear approximation.

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