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Modern hemostatic dressings such as QuikClot Gauze and Celox Gauze should be preferred to previous generations of hemostatic dressings, such as QuikClot ACS+. In vitro studies like ROTEM can provide valuable information about the mechanisms of action of hemostatic dressings. A combination of different mechanisms of action may increase the efficacy of hemostatic dressings.

NBER working papers are circulated for discussion and comment purposes. They have not been peer-reviewed or been subject to the review by the NBER Board of Directors that accompanies official NBER publications.

When improving industrial process chains in terms of productivity it is becoming more and more important to not only consider the static, but also the dynamic behavior of value streams. The effects of intended changes on production systems often are unknown and could underlie vast variations due to the planned outcome. In order to validate such changes before implementation, the use of material flow simulation is widely discussed in research and industrial practice. Such optimization projects usually require the collaboration of production system and simulation experts. Through the increased dissemination of various simulation tools on the market as well as multiple simulation methods available (discrete event, agent based and system dynamics) the actual selection of a suitable simulation setting is a challenging task. To support such optimization teams in the selection of an appropriate simulation method a decision making approach based on comparative criteria is shown and discussed in this article, concluding with a case study. 

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