A man in his 20s presented following a generalised tonic–clonic seizure on a background of a recent diagnosis of hepatitis B (HBV). During admission, he was severely hypertensive and imaging findings confirmed a diagnosis of posterior reversible leukoencephalopathy syndrome (PRES). The patient subsequently developed multiorgan involvement with an axonal sensorimotor neuropathy, vascular cutaneous lesions and multiple bilateral renal and splenic infarcts. Based on the 2012 Revised International Chapel Hill Consensus Criteria, a diagnosis of polyarteritis nodosa (PAN) with secondary PRES was made. The patient was given intravenous methylprednisolone, followed by a prolonged course of oral prednisolone, and tenofovir antiviral therapy to target HBV seroconversion. He made a good neurological recovery with resolution of imaging changes. This case highlights the importance of a low threshold for systemic screening for young patients presenting with PRES secondary to uncontrolled hypertension and the importance of viral screening, particularly for HBV.
BackgroundThere is a high number of non-epileptic attack disorder admission rate in the Lancashire teaching hospital which place a high demand on the service. To reduce the number of admission rate, treatment pathway is needed. If effective interventions are implemented there is a potential for the massive cost savings. It has been mentioned that an effective neurology assessment during the consulta- tion and referring to the physiotherapy and psychological services are ways to treat functional neurology disorders. One study highlighted the potential for psychological interventions as a favourable alternative to the current lack of treatment options offered to people with PNES.MethodsWe collated the data from 27 patients who are coded as NEAD for admission in Royal Preston Hospital in 2018.Result23–52% had an underlying history of psychological problems such as depression, anxiety and per- sonality disorders.57% had re-admission rate elsewhere. Maximum of 90 times admission as an inpatient in the Royal Preston Hospital.maythaenwe@gmail.com
BackgroundThe Prevalence of Multiple Sclerosis varies according to the geographical location and certain ethnic group. Genetic susceptibility to MS has also been linked to allelic variation It has been suggested that Viking genes’ can make people more susceptible to MS. Given the northern latitude and genetic background of the indigenous population, one might expect the higher prevalence of Multiple sclerosis.Cumbria Neurology Service: The Cumbria Neurology service has established in 2011, which used a single electronic patient record which has linked to the general practice. It is based within a community trust; and which is a single consultant-led service.ObjectiveTo study the prevalence of familial multiple sclerosis in Cumbria Region.ResultsOur estimated prevalence rate of multiple sclerosis is higher than a McKenzie et’s report. However, the data for the familial Multiple Sclerosis is lower than those of the global data (the data collecting is still ongoing).maythaenwe@gmail.com
Multiple Sclerosis is an autoimmune inflammatory disease of the central nervous system. Recent studies have revealed that both genetic and environmental factors, principally latitude affect the prevalence.In Cumbria, the vast majority of multiple sclerosis patients are under the care of a single consultant and specialist nurse-led service. Being community-based we believe there are very few people with MS who are not known to the service and this makes the population especially suitable for epidemiological study. The fact that the clinical team has access to the whole GP record through a shared clinical record enhances the data available research.Nursing staff in the MS team have prospectively recorded the presence or absence of a family history of MS, and where present the affected family members. We will report upon the prevalence of a family history in our cohort of patients with MS, Clinically isolated syndrome and Radiologically syndrome which numbers 1300, of whom 1150 have an established MS diagnosis. We will compare this with expected rates of familial MS based upon a review of existing literature.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.