Background: Breastfeeding, proper weaning practices, and newborn care play a crucial role in the health of a child. The objective of the study is to determine the availability of information regarding breastfeeding, newborn care and immunization and to find out about the attitude of women towards newborn care practices.Methods: A cross-sectional observational study was conducted in a tertiary health care centre in an urban area in Navi Mumbai, on primigravidae in their third trimester of pregnancy. The data was collected by a questionnaire, results were analysed by EpiInfo7.Results: 93% women knew the benefits of breastfeeding, 92% knew of exclusive breastfeeding. 90% would initiate breastfeeding immediately after delivery, 83% would not give prelacteal feeds. 75% would practise skin-to-skin contact and 95% would practise rooming-in technique. 44% would delay bathing the newborn. 95% women received TT immunisation. All agreed to vaccinate their child. 19% believed traditional practices like applying kajal to eyes, prelacteal feeds etc. to be hazardous.Conclusions: The knowledge pregnant women have about breastfeeding and newborn care is inadequate. There is a need for intervention measures such as behavior-change-communication and better health services, to equip mothers so they may provide optimal care to their babies.

Nearly 65%-95% of chronic kidney disease (CKD) patients have hypertension. Calcium-channel blockers are the first-line drugs for the treatment of hypertension, including hypertension with diabetes. This study aims to estimate the effect of an L-type calcium channel blocker (CCB), cilnidipine, on the renal function of hypertensive patients. Randomized control trials were selected from PubMed, Embase, Google Scholar, China National Knowledge Infrastructure (CNKI), Science Direct, Elton B. Stephens Company (EBSCO), Springer, Ovid, Cochrane Library, Medline, VIP, and Wanfang databases (from the date of databases' establishment till January 2022). Data were independently evaluated following the Cochrane risk-of-bias tool. The changes in serum creatinine (SCr), urinary protein excretion (UPE), urinary protein/creatinine ratio (UPCR), and estimated glomerular filtration rate (eGFR) before and after treatment, in percentages, were extracted for the meta-analysis. The mean difference (MD) and a CI of 95% were determined using RevMan 5.3 software. A total of 11 studies were analyzed. The standardized mean difference (SMD) between cilnidipine and L-type CCBs was -0.022, suggesting a reduced SCr with cilnidipine. For UPCR, the SMD value is 1.28. Although cilnidipine reduced UPCR in all four studies, the L-type CCBs reported a slight increase in UPCR. For eGFR, the SMD value was found to be 0.693. Cilnidipine had a more favorable effect on eGFR when compared to the L-type CCBs.While cilnidipine had similar effects on SCr to that of L-type CCBs, cilnidipine showed greater improvement in UPCR, UPE, and eGFR values.

The global proton pump inhibitors (PPIs) market was valued at US$ 2.9 billion in 2020 and is expected to exhibit a compound aggregated growth rate of 4.30% during the forecast period (2020-2027), as they are regularly prescribed for many gastrointestinal disorders, and the treatment usually lasts for a longer period. PPIs are usually combined with antiemetics and prokinetic drugs. The price of PPIs for the same combination varies a lot, which can lead to a lot of financial burden on the patients.