Objective: To determine the prevalence of depression in patients undergoing hemodialysis. Study Design: Cross-sectional study. Place and Duration: Institute of Kidney Diseases Hayatabad, Peshawar and PAF Hospital Islamabad for the duration from December 2021 to May 2022. Methodology: Two hundred and twenty patients on hemodialysis of either gender with ages 25-70 years were enrolled. Detailed demographics were recorded after taking informed written consent. Patients' Health Questionnaire-9 (PHQ-9) questions were used to determine the frequency of depression. Severity of depression was also examined. Data was analyzed by SPSS 24.0. Results: There were 135 (61.36%) males while 85 (38.64%) patients were females. Mean age of patients was 46.85±12.38 years. Mean time duration of hemodialysis was 5.25±2.46 years. Depression was found in 160 (72.73%) patients, among them 30 (13.64%) patients had mild, 75 (34.09%) had moderate and 55 (25%) had severe depression. Patients on hemodialysis less than 5 years found more depressive as compared to >5 years. (p-value <0.05). Conclusion: It is concluded that the prevalence of depression in patients of hemodialysis was high.

Background and Aim: Restless legs syndrome (RLS) is a prevalent neurological disease that is frequently misdiagnosed due to comparable signs and symptoms to other disorders such as diabetes, migraine, and cardiovascular disease. RLS may deteriorate with age, and it is more frequent in women than in males. The incidence of RLS varies from 6.6% to 80% in the general population. The present study aimed to assess the RLS in patients on hemodialysis. Patients and Methods: A questionnaire based study was conducted on 116 consecutive hemodialysis patients in the Department of Neurology and Nephrology of Institute of Kidney Diseases Hayatabad, Peshawar and PAF Hospital, Islamabad for the Duration from June 2022 to December 2022. Patients’ history included a history of drug, predialysis duration, and hemodialysis duration. Data was obtained using a standardized questionnaire that includes demographic variables such as personal history, family history, disease history, and smoking history.