This meta-analysis aimed to determine the pooled association between polycystic ovary syndrome (PCOS), hypothyroidism, and fibrocystic breast changes. We searched important databases, including PubMed (Medline), Scopus, Web of Science, and Embase to retrieve all relevant studies published from 1990 to April 2021. The bias risk of selected articles was assessed based on the JBI checklist. Our search strategy yielded a total of 487 articles from the international databases. After screening their full-texts, 6 articles met the inclusion criteria and were considered for meta-analysis. The effect of PCOS on the incidence of fibrocystic breast changes was 2.49 (95% CI 1.85–3.34). Also, the effect of hypothyroidism on the incidence of fibrocystic breast changes was 1.90 (95% CI 0.92–3.93). The results showed that women with PCOS were at higher risks to develop fibrocystic breast changes.

Background It has been assumed that perinatal factors such as multiple pregnancies may affect subsequent breast cancer risk in the mother. Considering the inconsistencies in the results of case-control and cohort studies published in the world, this meta-analysis was conducted in order to determine the exact association between multiple pregnancies (twins or more) and the breast cancer incidence. Methods This study was performed as a meta-analysis based on PRISMA guidelines by searching the international databases of PubMed (Medline), Scopus, and Web of Science as well as by screening selected articles based on their subject, abstract and full text. The search time was from January 1983 to November 2022. Then the NOS checklist was used to evaluate the quality of the final selected articles. The indicators considered for the meta-analysis included the odds ratio (OR) and the risk ratio (RR) along with the confidence interval reported in the selected primary studies. The desired analyzes were performed with STATA software version 17 to be reported. Results In this meta-analysis, 19 studies were finally selected for analysis, which fully met the inclusion criteria. Of these, 11 were case-control studies and 8 were cohort ones. Their sample size was 263,956 women (48,696 with breast cancer and 215,260 healthy) and 1,658,378 (63,328 twin or multiple pregnancies and 1,595,050 singleton pregnancies), respectively. After combining the results of cohort and case-control studies, the effect of multiple pregnancies on the breast cancer incidence was equal to 1.01 (95% CI: 0.89–1.14; I2: 44.88%, P: 0.06) and 0.89 (95% CI: 0.83–0.95; I2: 41.73%, P: 0.07), respectively. Conclusion The present meta-analysis results showed, in general, multiple pregnancies were one of the preventive factors of breast cancer.

Background and Aims The aim of this study was to investigate the prevalence and desire towards performing elective cosmetic surgery and its relationship with socioeconomic, mental, and spiritual health in Sanandaj, the capital of Kurdistan province in the west of Iran. Methods This cross‐sectional descriptive‐analytical study was performed on 492 subjects in Sanandaj using multistage sampling method. Data collection tools included two checklists and two questionnaires. Data analysis was performed using the Chi‐square test and multiple logistics regression model by the help of SPSS software version 20. Results The mean (standard deviation) age of participants was 32.58 (9.67) years. The prevalence of cosmetic surgery and the desire to perform it were 12.8% ( n = 63) and 19.1% ( n = 94), respectively. The most common type of cosmetic surgery was rhinoplasty with 5.5% ( n = 27). The prevalence of symptoms of mental disorders among people with cosmetic surgery and people willing to perform cosmetic surgery was significantly higher than all subjects ( p < 0.001). Female gender (odds ratio [OR] = 1.98; 95% confidence interval [CI]: 1.06–3.68) and having mild (OR = 3.01 95% CI: 1.06–3.68) and moderate to severe symptoms of mental disorder (OR = 7.59; 95% CI: 3.90–14.75) were among the influential variables on performing cosmetic surgery. Conclusion Both the prevalence and desire towards performing cosmetic surgery are high in Sanandaj and this needs the attention of health policy makers. Designing targeted interventions with an emphasis on the findings of this study is proposed to reduce these practices.

Introduction: Epidemiological investigation of Mortality is essential for health policy control of risk factors and disease. Obtaining this information is the essential basis for planning, management and evaluation, and accountability in countries' health sector. Studying Mortality and its etiologic factors are the most appropriate strategies to reduce Mortality. Objective: The study aimed to investigate the causes of death and prognostic factor of death in patients referred to the emergency department. Method: this was a cross-sectional study from 2016 to 2018 at Tohid Teaching Hospital in Sanandaj. All history and clinical examination data and Para clinical study of the patients who had expired in the first 24 hours after emergency department admission were collected in questionnaire sheets. The data was interred into spss software and analyzed using descriptive statistics frequency and percentage. Result: 73 patients, 43.8% female, and 41% male with a mean age of 63.6 years old 20-90 evaluated in our study. The first common chief complaint of the patients was chest pain 24.7%, and the most common past medical disease in the patients was hypertension 28.8% also the first common reason of death was ischemic heart disease 31.5%.43.8% of patients had abnormal electrocardiograms, 19.2% had dysrhythmias, and 24.6% had ischemic changes. Laboratory results also showed that the prevalence of sodium imbalance was 53.5%, and potassium and calcium imbalance were 37.9%& 80.8%. Also, 80.8% of patients had PH abnormalities, 30.1% acidosis, and 50.7% alkalosis. Conclusion:According to the results, it can be concluded that patients with cardiac problems or a history of cardiovascular disease are the highest risk patients and should be considered more serious. Also, electrolyte and blood gas imbalance were prevalent in these patients.