Lung cancer is the biggest cause of cancer mortality worldwide and a major impediment to extending life expectancy. In comparison to other cancers, it has a relatively poor survival rate. In this paper, we have developed a mathematical model for lung cancer based on biological phenomena using nonlinear ordinary differential equations and analyzed it both analytically and numerically. According to the findings, CD8+ T cells and dendritic cells have a role in tumor cell variety. Surgery and chemotherapy have been used as treatment options, and we have observed that three doses of chemotherapy after surgery had the greatest results after examining several treatment options. During the treatment period, the cycle of each chemotherapy has been taken every 4 weeks, and the first dose has been taken after 28 days of surgery. Finally, we have evaluated the various starting dates for the best treatment choice and discovered that the patient who begins treatment sooner has a better probability of surviving.
Soil salinity is the major limiting factor restricting plant growth and development. Little is known about the comparative and combined effects of gibberellic acid (GA3) seed priming and foliar application on maize under salt stress. The current study determined the impact of different concentrations of GA3 on morpho-physiological and photosynthetic attributes of maize seedlings under salinity stress treatments (no salinity and severe salinity-15 dSm-1). The GA3 treatments consisted of 1mM, 2mM, 3mM, 4mM and 5mM GA3 seed priming and exogenous application in salt condition. Salt stress particularly at 15 dSm-1 reduced the length of shoots and roots, fresh and dry weights, chlorophyll, lycopene, beta-carotine and carotenoid contents in maize plants. Nevertheless, the application of GA3 improved maize growth under salt stress. Compared with salt, the 2mM GA3 treatment (T4) recorded the highest increase in roots and shoots length, roots fresh and dry weights, shoots fresh and dry weights, chlorophyll content under salt stress compared to other concentrations. These results indicated that 2mM GA3 priming and exogenous application could be used as an effective tool for improving the maize growth and development in salt contaminated soils.
Aim: Uniform and rapid germination and growth is a major barrier to successful crop production of bitter gourd, a major summer vegetable of Bangladesh. Seed priming with different signaling molecules can efficiently confer this problem. Therefore, the present study was conducted to explore the potentiality of different signaling molecules such as salicylic acid (SA) and gibberelic acid (GA3) to increase germination and growth of bitter gourd.
Place and Duration of the Study: The study was conducted in the Department of Seed Science and Technology, Bangladesh Agricultural University, from September-October, 2022.
Methodology: The bitter gourd seeds were soaked in 1mM, 2mM and 3mM GA3, and 3mM, 6mM and 9mM SA solutions for 1 hour. The untreated seeds were used as control. Seeds were germinated in petri dishes and data on germination was collected. Then seedlings were transplanted to pot after 7 days to record growth parameters at 15th day of establishment.
Results: The experiment's findings indicated that lower concentrations of SA and GA3 had a beneficial effect, however greater levels significantly reduced the bitter gourd's ability to germinate and develop in comparison to the control. Findings of the study showed priming concentrations of 3mM SA, 6mM SA, and 1mM GA3, markedly improved the germination percentage, shoot and root length, seedling vigour, and fresh and dry weight of the shoot and root, RWC of bitter gourd.
Conclusion: Pretreatment with SA and GA3 was observed to be relatively more efficient in increasing germination of bitter gourd compared with control. Overall, this study suggests that bitter gourd seed priming 3mM SA, 6mM SA, and 1mM GA3 can improve germination and growth.
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