Background: Anesthesia is quite remarkable and attenuation of pressor response is one of the most keenly researched subjects in the field of anaesthesiology, the reason being the non-availability of a ‘procedure/drug of choice’ for the same. Patients with arterial hypertension generally exhibit excessive pressor response to stress such as laryngoscopy, intubation, surgical incision and extubation, which can lead to arrhythmias, myocardial ischemia and cerebrovascular accidents. Exchange extubation with LMA Supreme can be used to overcome or blunt the excessive pressor response following extubation. Objective: To compare the hemodynamic changes during traditional awake extubation and extubation using LMA supreme in controlled hypertensive patients. Methods: The prospective study was carried out in the department of Anaesthesiology, Shaheed Tajuddin Ahmad Medical College Hospital, Gazipur, Bangladesh from January to December-2021. Fifty (50) patients were randomized by permuted blocks into two groups. After complete pre- anesthetic check-up and investigations. Controlled hypertensive patients with ASA (American Society of Anesthesiologists) grade II, between the age of 17 and 65 years, undergoing elective, non-oral surgery were included in the group. Hemodynamic stress response between traditional awake extubation of the endotracheal tube (ETT) and that following exchange extubation of ETT by using a laryngeal mask airway (LMA Supreme) in terms of Post Extubation Heart Rate (H.R), Systolic Blood Pressure (S.B.P), Diastolic Blood Pressure (D.B.P), Mean Arterial Pressure (MAP), to determine whether this method is easy to perform, the amount of experience needed to perform the exchange well and to calculate the time delay in extubation caused by adopting this method. Results: There was highly significant increase in pulse rate in Group A (ETT Group) as compare to LMA SupremeTM group, which was statistically significant till 15min. of extubation. Statistically ...........

Background: Gastric cancer (GC) is one of the leading causes of mortality and morbidity and adds significantly financial burden to patient and their family on healthcare. The incidence of gastric cancer continues to increase in Bangladesh; therefore there is unmet need of promising treatment modalities. Objective: To investigate the survival of patients undergoing gastric cancer surgery with epidural combined with general anesthesia (EGA) and general anesthesia alone (GA). Methods: A retrospectively observation study was carried out at the Dept. of Anesthesia, National Institute of Cancer Research & Hospital (NICRH), Mohakhali, Dhaka, Bangladesh from June 2021 March 2022. 451 patients with gastric cancer who were scheduled for radical resection. Propensity score matching was performed at a 1:1 ratio between GA (n=75) and EGA (n=75) to reduce selection bias. Univariate and multivariate analyses were used to identify factors significantly correlated with recurrence and/or metastasis and prognosis. The 3-year overall survival rates of patients receiving EGA and GA alone were compared. Results: After the propensity scores were matched, there were 75 patients who underwent EGA and 75 patients who underwent GA. For the entire population, reconstruction type, pN stage, and complications were significantly correlated with prognosis based on multivariate analyses. For patients with a recurrence and/or metastasis, lymphadenectomy and pN stage were shown to be independent prognostic factors by multivariate analysis. Conclusions: In summary, patients might benefit from EGA as a result of better analgesic and anti-inflammatory effects, fewer postoperative complications, higher safety, and a lower rate of metastasis and recurrence is conducive to postoperative recovery in patients with gastric cancer.