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In the logistic regression analysis, after adjusting for potential confounders, such as abnormal WBC count, use of intravenous fluid, patient with fatal outcome more often presented with hypernatremia (odds ratio = 16.48, 95% confidence interval = 2.21 -123.12; p = 0.006), lobar consolidation (odds ratio = 19.9, 95% confidence interval = 2.99 -132.80; p = 0.002), hypoxemia (odds ratio = 14.78, 95% confidence interval = 1.38 -157.90; p = 0.026) and severe under-nutrition (odds ratio = 7.57, 95% confidence interval = 1. 24 -46.11; p = 0.028). CONCLUSIONS: Our data suggest that children under-five with clinical sepsis who present with lobar pneumonia, hypoxaemia, severe acute malnutrition and hyperntaemia are at higher risk of death and identification of these simple factors may help clinicians to take prompt initiative for the aggressive management of such children especially in a resource-limited setting like Bangladesh.

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