Introduction:  Oral cavity cancer is the 11th most common cancer worldwide, and the incidence rate of lip & oral cavity cancer in Bangladesh in 2020 was 8.9%. The National Institute of Cancer Research and Hospital (NICRH) is a specialized hospital for cancer patient care where all treatment modalities are available. This study was conducted in the faciomaxillary surgical oncology department (FMSO) to see the patient profile and management of oral cancer patients at NIRCH. Materials and methods: This observational study was carried out from January 2017 to December 2020 with hitopathologically proven oral cancer patients. Data of outdoor patients were collected from the OPD and tumor board registers, and indoor patient’s data were collected from the discharge register.  Relevant variables were included in the data collection, such as epidemiological features (age, sex) and clinicopathological data (primary site of tumor, disease pattern, TNM staging, presentation status, management of patients by tumor board decision, and surgical management). Collected data were summarized and analyzed by statistical package for the social science SPSS (version 24.0) and results were presented in table, chart, and graph form. Results: A total of 6869 patients were enrolled in the study, where 55% were female and 45% were male, with a male to female ratio of 0.82:1. Buccal mucosa was the most common site (44%) followed by lower gingivo-buccal sulcus (21%). Eighty-eight percent of the total cases were squamous cell carcinoma. Early-stage lesions were only 6% whereas advanced-stage lesions were 94%.  Among preoperative patients, 1992 (29%) were operable and 4877 (71%) were inoperable. The tumor board decided nearly 50% of patients for chemo-radiation, 10% for surgery and radiotherapy each. Among the operable patients, only 244 (20%) were operated on in our department in a four-year period. Conclusion: It is evident from this study that most of the patients present in the advanced stage illustrate the necessity for the inclusion of oral health care in primary health care by the government for early detection of oral cancer in Bangladesh. Update Dent. Coll. j: 2022; 12(2): 27-31

Introduction: Lip and oral cavity cancer is the third and fifth most frequent cancer for men & women respectively in Bangladesh. Locoregional recurrence after primary surgery is common for oral cancer due to aggressive local invasion and metastasis. The objective of this study was to analyze the predictors of locoregional failure in a tertiary center hospital. Materials and Methods: A prospective cohort study was designed to analyze the presence of recurrences of OSCC patients after surgery. The purposive sampling technique was used to include patients in the study. Excision of the primary tumor was done with neck dissection followed by reconstruction with local or regional flap. The variables considered were demographic information, site, TNM stage at diagnosis, margin status, lymph node metastasis, perineural invasion, recurrence, and the adjuvant therapy used for disease control. Patients were followed up by hospital revisits or phone calls and necessary information was collected through a standardized data collection sheet.   Results: A total of 39 patients were included for data analysis. The male to female ratio was 1:2 and the most common primary site was mandibular alveolar mucosa (31%). Nearly 90% of patients were admitted with stage ׀׀׀ or ׀ᴠ lesions and tumor margin was positive in 21% of cases. Lymph node metastasis and perineural invasion were identified in 64% and 23% of cases respectively. Recurrence developed in 14 patients (36%) during the average follow-up of 13 months. Recurrences were more common in females (42%) and Postoperative histopathology showed a positive margin, perineural invasion, and N3 neck node. Univariate logistic regression analysis for locoregional recurrence showed no significant association between the variables and recurrence. Patients with clinically palpable lymph node, grade 2 lesion, presence of perineural invasion, presence of co-morbidity, patients who did not receive any adjuvant therapy, and patients who had metastatic neck node showed an increased odds ratio (OR>1). Conclusion: The clinicopathologic and treatment-related factors of recurrence in OSCC were explored in this study. Although no significant association was identified between the variables and recurrence of lesions, a high recurrence rate was observed in a shorter span of the follow-up period. Update Dent. Coll. j: 2022; 12 (1): 12-16