immunoproliferative small intestinal disease is considered as a rare condition and has endemicity inMediterranean countries and often associated with campylobacter jejuni infection. This conditionvaries in severity from benign to frankly malignant. Prolonged remission can be obtained with longterm antibiotic therapy but chemotherapy is required for those who have aggressive disease. Bangladeshidata on IPSID is sparse. Here our patient 21 years old male presented with chronic diarrhoea, occasionalvomiting, severe weakness and significant unintentional weight loss. He had cachectic body built,bipedal edema, easy bruising, glossitis with angular stomatitis. His upper GI endoscopy showed multiplenodular lesion in the duodenum. Biopsy was taken from nodular lesion and sent for histopathology,geneXpert and culture. Histopathology revealed IPSID. He was treated with tetracycline and improvedclinically. J MEDICINE 2022; 23: 84-86

Eosinophilic esophagitis (EoE) is characterized by eosinophilic infiltration of the esophagus. It has become increasingly recognized over the last decade. It is associated with a variety of esophageal symptoms such as dysphagia, food impaction and chest pain. Diagnosis of the disorder is dependent on the patient’s clinical presentation and histological findings on esophageal mucosal biopsies. Eosinophilic esophagitis (EoE) is being recognized increasingly all over the globe; however Bangladeshi data on eosinophilic esophagitis is sparse and no case report has so far been made. In our this case report a 14-year-old boy presenting with dysphagia for last few years with weight loss was diagnosed as eosinophilic esophagitis after biopsy from esophageal stricture and ulceration. He was managed initially with enodoscopic dilatation followed by steroids & improved clinically. J MEDICINE JUL 2019; 20 (2) : 109-111