Globally, breast cancer is the most common cancer and the second leading cause of cancer-related death among women. Surgery, chemotherapy, hormonal therapy, and radiotherapy are currently available treatment options for breast cancer therapy. However, chemotherapy, hormonal therapy, and radiotherapy are often associated with side effects and multidrug resistance, recurrence, and lack of treatment in metastasis are the major problems in the treatment of breast cancer. Recently, dietary phytochemicals have emerged as advantageous agents for the prevention and therapy of cancer due to their safe nature. Ellagic acid (EA), sulforaphane (SF), and ursolic acid (UA), which are found in widely consumed fruits and vegetables, have been shown to inhibit breast cancer cell proliferation and to induce apoptosis. This review encompasses the role of EA, SF, and UA in the fight against breast cancer. Both in vitro and in vivo effects of these agents are presented.

Diabetics Mellitus is a major problem for city people worldwide. The objective of this study is finding the anti-diabetic and anti-hyper lipidaemic activity by using Carica papaya leaves. This leaves are not generally eaten but this leaves were eaten during dengue fever. The leaves extract is used for the treatment of diabetes and cancer. This leaves were collected from different place of Bangladesh and made methanolic extract then this extract was feed four groups of mice. The results showed that there was a significant (p<0.001 to p<0.05) reduction in blood glucose concentration (mmol/L) by the methanolic extract of C. papaya leaves at dose 100 mg/kg, 200 mg/kg and glibenclamide (used as standard) 5mg/kg body weight. C. papaya leaves extract also regulated the serum lipid profile levels significantly (p<0.001) at same dose in experimental model of diabetes mellitus. The level of serum SGPT, SGOT and CRP were also seen change to the normal level notably (p<0.001) by the oral administration of methanolic extract of C. papaya leaves. In conclusion this research finding indicate that the methanolic extract of Carica papaya leaves contains bioactive substances with hypoglycemic potency.

Globally, Breast cancer is a complex and common disease. 12.5 % of all new annual cancer cases worldwide. In 2020 there were 2.3 million women with breast cancer diagnosed and 685,000 died globally. For long time, breast cancer treatments options include surgery, chemotherapy, hormone therapy and radiotherapy. However adverse effects from treatment options are frequently reported and multidrug resistance, fever, weakness, allergy and the absence of treatment for metastasis are the main issues with breast cancer treatment. Due to their safety, dietary bioactive molecules have become effective tools for the treatment and prevention of cancer cell lines and animal models in recent years. It has been demonstrated that the compunds curcumin, diallyl sulfide, quercetin and gallic acid which are used as Indian spice and widely consumed fruits, suppress the growth of breast cancer cells and trigger apoptosis. The effects of curcumin, diallyl sulfide, quercetin and gallic acid in the combat against breast cancer are covered in this review. These agents have been shown to have effects both in vitro and in vivo.