Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed on 356 randomly selected thalassemia patients. Participants were invited to face-to-face interviews. Descriptive statistics (frequencies and percentages), independent t-test, ANOVA, and multivariate (linear and logistic regression) analysis was performed to analyze the data. Our demographic data showed that among 356 patients, 54% and 46% were male and female, respectively, with an average age of 19.75 (SD = 8.02) years. Most were transfusion-dependent (91%), 26% had comorbidities, and 52% were from low-income families. In the case of HRQoL, male patients showed significantly higher scores of bodily pains and physical health summaries than female patients. Lower income, high blood transfusion status, disease severity, comorbidities, and medical expenses (p < 0.05; CI 95%) are significantly associated with lower SF-36 scores. This study found an association between lower income, blood transfusion, disease severity, comorbidities, as well as medical expenses, and the deterioration of HRQoL among TP. Male patients experienced poorer HRQoL than females. National action plans are required to guarantee the holistic welfare of thalassemia patients.

We are proud to present the June issue, Vol. 11 of our online journal MIJST, which focuses on the cutting edge of technical excellence and its profound effects on our lives. We encourage you to go through the virtual halls of technical excellence, where engineers from all over the world congregate to collaborate, inspire, and alter the world we live in, as part of our unrelenting dedication to expanding the limits of human achievement. Together, let's use engineering to pave the way for a better, more intelligent, and more sustainable future.I would like to take this opportunity to thank the editorial team of the journal for all of their efforts in creating the current edition. My deepest gratitude is extended to all of the reviewers of the papers in this issue for their priceless recommendations and remarks. All of the National and International Advisory Board Members of MIJST have my sincere gratitude for their constant advice and recommendations aimed at raising the caliber of MIJST.

Bangladesh is an agrarian-based developing economy that has recently achieved accelerated economic growth via its industrial sector. Such levels of industrial development have increased energy demands, with negative impacts not only on human health but also on agricultural land and biodiversity. these forms of environmental degradation pose risks to rice production, the main agricultural crop, due to associated declines in soil, water, and air quality. this study intends to analyze rice farmers' level of awareness and perception of the impacts of environmental degradation, and factors influencing the awareness. Primary data were collected from 300 rice producers in six districts in Bangladesh during August-September 2019 by a structured questionnaire, where agricultural arable lands have been degraded the most. A multinomial logit model has been used to explore the relationship among key factors. Farmer awareness levels varied according to age, farming experience, farm household income, adoption of inclusive agribusiness, access to extension workers, and distance from the nearest industrial zone. there was spatial heterogeneity among rice grower perceptions of the impacts of environmental degradation. Government guidance and some socio-economic factors could reshape and improve the farmer awareness levels on natural degradation, to facilitate the maintenance of farm operations and food security nationwide.