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In periodontitis, one of the major pathologic patterns is an increased production of reactive oxygen species (ROS). Reactive oxygen species are produced by polymorph nuclear cells as an inflammatory response to invading pathogenic bacteria. This imbalance among the production of free radicals and local antioxidants results in periodontal tissue destruction and a state of oxidative stress develops. In recent years, beneficial effects of antioxidants against various chronic disorder induced by oxidative stress have received much attention. This review is intended to summarize the role of dietary antioxidants in prevention of periodontal disease.

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