Papillary thyroid cancer is the most common thyroid malignancy, and although metastatic spread is typically confined to regional lymph nodes, there are rare documented cases of distant spread of disease. Distant metastases of differentiated thyroid cancer are unusual; lung and bones are the most frequently affected sites. Soft tissue metastases are extremely rare. Here we present an unusual case of soft tissue metastasis of papillary thyroid cancer to skeletal muscle. Soft tissue metastasis is rarely seen in differentiated thyroid carcinoma. Differentiated thyroid carcinoma, although generally clinically indolent, may occasionally develop distant metastases and even manifest itself as a metastatic tumour.

Adrenal schwannoma is a rare type of adrenal incidentaloma and is found in the medulla. There have been only 33 reported cases worldwide. We present a 56-year-old female referred to our institution for a history of abdominal discomfort and a left adrenal solid mass incidentally discovered in USG. Patient underwent surgical excision of the tumour. Histopathologic examination showed a neoplasm composed of cells arranged in interlacing fascicles with alternating hyper and hypo cellular areas, Immunohistochemistry (IHC) showed positive for S100 compatible with adrenal schwannoma.

BACKGROUND 5% of all ovarian cancers are granulosa cell tumour. However, they are the most common subtype of ovarian sex-cord tumours (70%). They usually occur in young women and are usually detected at an early stage. The aim of this study was to report the clinical characteristics of GCT patients and to identify the recurrence rate. MATERIALS AND METHODSAll cases of GCTs, treated at Caritas Cancer Institute between 2003 and 2007, were retrospectively included. Kaplan-Meier's statistical method was used to assess the relapse-free survival and the overall survival. RESULTS20 patients with GCT were included in the study. The mean age was 56 years (36-76 years). Patients mainly presented with abdominal mass and/or pain. Mean tumour size was 20 cms. The majority of patients had a stage I disease. Two out of three patients with stage IV disease had liver metastasis. Stage I disease and low-to-intermediate mitotic index were associated with a better prognosis in univariate analysis but were not independent prognostic factors. CONCLUSIONThis tumour has long natural history and late relapses. That's why a long active follow-up is recommended. In Indian patients, hepatic metastases were more frequent than other series. The prognosis remains good and ideal cytoreduction is an important prognostic factor.