A 57-year-old woman who had undergone a pancreaticoduodenectomy operation two weeks previously for distal cholangiocellular carcinoma was referred to our department due to prolonged and excessive drainage (>500 ml/day) from her surgical drain. Initial examination of the patient revealed no signs of peritonitis or sepsis. Endoscopic examination revealed a suture dehiscence over almost half of the complete circumference of the gastrojejunal anastomosis ( Figure 1A). Following irrigation of the suture line for better visualization, the opposing wound lips were traumatized by forceps to facilitate the re-epithelization process. Afterwards, complete repair was achieved using a total of 11 hemoclips that were carefully applied along the anastomosis ( Figure 1B). Anastomotic leakage began to reduce after the endoscopic procedure and ceased after the third day of hemoclip application. A follow-up endoscopy two months later showed an intact anastomosis line with no signs of leakage (Figure 2).Among a long list of complications currently recognized after pancreaticoduodenectomy, anastomotic leakage is a serious one, with an incidence of 8-20% in recent studies (1). Although the majority of patients with anastomotic leakage can be successfully treated by conservative means, serious consequences such as bleeding and severe intra-abdominal infection may occur (2,3). Moreover, delayed gastric emptying, re-laparotomy, prolonged hospitalization, and added costs are also unwanted related sequelae. Conventional management of clini- Successful endoscopic management of anastomotic dehiscence with hemoclips application after pancreaticoduodenectomyPankreatikoduodenektomi sonras› geliflen anastomoz kaça¤›n›n hemoklips uygulamas› ile tedavisi Manuscript