Bone age is estimated in pediatric medicine for medical and legal purposes. In pediatric medicine, it aids in the growth and development assessment of various diseases affecting children. In forensic medicine, it is required to determine criminal liability by age, refugee age estimation, and child-adult discrimination. In such cases, radiologists or forensic medicine specialists conduct bone age estimation from left hand-wrist radiographs using atlas methods that require time and effort. This study aims to develop a computer-based decision support system using a new modified deep learning approach to accelerate radiologists' workflow for pediatric bone age estimation from wrist radiographs. The KCRD dataset created by us was used to test the proposed method. The performance of the proposed modified IncepitonV3 model compared to IncepitonV3, MobileNetV2, EfficientNetB7 models. Acceptably high results (MAE=4.3, RMSE=5.76, and R2=0.99) were observed with the modified IncepitonV3 transfer deep learning method.

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ÖzÜlkemizde endemik zoonotik hastalık olan bruselloz çeşitli klinik tablolar ve komplikasyonlarla karşımıza çıkabildiğinden tanı ve tedavisinde zorluk yaşanabilen bir hastalıktır. Bakteriyemi yapabilme özelliği nedeniyle Brucella cinsine ait bakteriler çok çeşitli organlara yerleşip atipik klinik formlarda karşımıza çıkabilir. Brucella türlerinin neden olduğu kolesistit nadir görülen bir tablodur.Bu olgu sunumunda tanısında oldukça zorlanılan, tanısı dren kültüründe Brusella melitensis üremesi ile konulan seronegatif bruselloza bağlı akut kolesistit olgusu sunuldu. Akut kolesistit ön tanısı ile opere edilen postoperatif dönemde ateş yüksekliği ve lökopeni gelişen hastada, negatif Brusella serolojisine rağmen kan kültüründe ve dren kültüründe Brucella melitensis tespit edilmiştir. Hasta 6 haftalık doksisiklin 2x100 mg/gün ve rifampisin 1x600 mg/gün tedavisi sonrası sekelsiz iyileşmiştir. Anahtar kelimelerBruselloz; Akut Kolesistit; seronegatif Bruselloz; Brucella melitensis. Abstract Brucellosis, which is an endemic zoonotic disease in our country, may present difficulties in diagnosis and treatment since it may present with various clinical manifestations and complications.Because of its ability to make bacteremia, bacteria of the genus Brucella can be placed in wide organs and can be seen in atypical clinical forms. Cholecystitis caused by Brucella species is a rare condition. In this article, we present a case of acute cholecystitis related to seronegative brucellosis with Brucella melitensisdespite negative Brucella serology, Brusella melitensisdetected in blood and drain cultures of the patient who operated with the preliminary diagnosis of acute cholecystitis, developed fever and leukopeniain the postoperative period. The patient recovered without sequelae after 6 weeks of doxycycline 2x100 mg / day and rifampicin 1x600 mg / day treatment.

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PurposeAcute appendicitis is one of the most common surgical pathologies. Geriatric appendicitis patients have more complicated appendicitis, which leads to higher morbidity and mortality rates. Sarcopenia is an emerging concern among geriatric patients and has been shown to have a negative impact on patients undergoing emergency surgery.Our primary aim in this study is to reveal the predictive value of computerised tomography (CT)-assessed sarcopenia for complicated appendicitis in geriatric patients.Methods154 acute appendicitis patients of geriatric age with preoperative contrast-enhanced abdominal CT were analysed. Patients’ age, gender, appendicitis status and BMI values were analysed. CT-assessed sarcopenia value, SMI (Skeletal Muscle Index) and related measurements were evaluated by two senior radiologists. Statistical analysis was conducted by descriptive and inferential statistical methods, as applicable.Results52% of the patients had complicated (n=80) and 48% had uncomplicated appendicitis (n:74). There was no difference in gender distribution between uncomplicated and complicated cases. There was a statistically significant difference between uncomplicated and complicated cases in terms of BMI, SMI and muscle area values (p<0.05). Moreover, there was a statistically significant difference for subcutaneous fatty tissue area between uncomplicated and complicated cases (p<0.10). The cut-off point by ROC analysis was conducted for CT-assessed sarcopenia index and showed 71% sensitivity and 52% specificity (p=0.042). ConclusionGeriatric patients who have lower BMI, decreased muscle area and CT-detected sarcopenia have an increased risk of complicated appendicitis. Surgeons should be aware of factors leading to complicated appendicitis, which may cause higher morbidity and mortality rates in elderly patients.