ABS TRACT Thyroid tuberculosis is a very rare condition with a rate of 0.1-1.15% even in countries with a high prevalence of tuberculosis. In this presentation, we evaluated the management of a patient with a preoperative diagnosis of benign tissue and a pre-diagnosis of multinodular goiter with compression symptoms. After thyroidectomy of our patient who had no special history due to the detection of Langerhans giant cell caseified granuloma-thyroid tuberculosis, postoperative thyroid replacement therapy and infectious diseases outpatient control were planned. Thyroid tuberkulosis is not easy to diagnose because there are no specific symptoms. If no other foci are detected after total thyroidectomy, close follow-up is recommended without additional antituberculosis therapy. As the incidence of tuberculosis increases worldwide, thyroid tuberculosis as the unusual involvement of extrapulmonary tuberculosis; it should be kept in mind in the differential diagnosis of nodular lesions of the thyroid gland.