here are many questions and concerns about the coronavirus disease 2019 (COVID-19), including its implications for breastfeeding. 1 This commentary draws on a statement and recommendations recently issued by the Regional Office for Europe of the World Health Organization with the contribution of the European Pediatric Association-Union of National European Pediatric Societies and Associations and other main European pediatric organizations. 1 Our aim is to provide pediatricians with further guidance on breastfeeding and related safety measures during COVID-19, particularly in instances where a mother has or may have COVID-19. The COVID-2019 epidemic, caused by severe acute respiratory syndrome coronavirus 2, was first identified in Hubei Province China in December 2019, and has subsequently spread globally, placing extensive pressure on health systems and posing a major public health challenge worldwide. 2 On March 11, 2020, the World Health Organization (WHO) declared the outbreak a pandemic. 3 At the time, little was known about COVID-19 or its effects on the general population, and even less was known about how it could influence specific populations such as pregnant women, infants, or children. Reports show that children at all ages are sensitive to COVID-19, with no significant gender difference. 4 Clinical manifestations of children's COVID-19 cases are less severe than in adults' patients, and a review of 72 314 cases by the Chinese Center for Disease Control and Prevention showed that <1% of the cases were in children <10 years of age. 5 Additional information about COVID-19 infection among children is increasing over time, but questions remain, including questions about breastfeeding, particularly in instances when a mother may be infected with COVID-19. 6,7 The protection, promotion, and support of breastfeeding are a priority for public health and WHO has been continuously compiling evidence on the effect of COVID on mothers and children. 3,8,9
Women with PCOS have increased serum prolidase activity and oxidative stress. It might be hypothesized that elevated serum prolidase activity and oxidative stress may be associated with increased cardiovascular risk in PCOS and/or menstrual irregularities associated with this syndrome.
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