This study aimed to investigate the spatial autocorrelation between precipitation and vegetation indices in the Bandar Abbas basin. For this purpose, the vegetation indices of DVI, EVI, IPVI, NDVI, NDWI, RVI, SAVI, TCI, VCI, and VHI were derived from Landsat satellite images over 20 years were studied. Precipitation data corresponding to rain gauge stations was extracted. The Pearson correlation coefficient and the GI * and I indices were used to investigate the relationship between precipitation and spatial autocorrelation. Moreover, the Pearson correlation coefficient was used to investigate the relationship between precipitation and vegetation indices, and the GI * and I indices was used to correlate spatial autocorrelation patterns. The results showed that SAVI, VHI, VCI, and NDWI were most correlated with precipitation among the Bandar Abbas basin's vegetation indices, with the SAVI index being more closely correlated than the others. However, precipitation had the least impact on the TCI index. The spatial autocorrelation of rainfall with the vegetation indices, except for the IPVI index, had a scattered pattern in the study area’s southern and eastern parts. Of the indices studied in terms of spatial pattern, the IPVI and NDWI indices formed a positive spatial correlation pattern with precipitation over a greater spatial range.