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Introduction Post-operative nausea and vomiting (PONV) is a common problem after sleeve gastrectomy. In recent years, following the increase in the number of such operations, special attention has been paid to preventing PONV. Additionally, several prophylaxis methods have been developed, including enhanced recovery after surgery (ERAS) and preventive antiemetics. Nevertheless, PONV has not been completely eliminated, and the clinicians are trying to reduce the incidence of PONV yet. Methods After successful ERAS implementation, patients were divided into five groups, including control and experimental groups. Metoclopramide (MA), ondansetron (OA), granisetron (GA), and a combination of metoclopramide and ondansetron (MO) were used as antiemetics for each group. The frequency of PONV during the first and second days of admission was recorded using a subjective PONV scale. Results A total of 130 patients were enrolled in this study. The MO group showed a lower incidence of PONV (46.1%) compared to the control group (53.8%) and other groups. Furthermore, the MO group did not require rescue antiemetics, however, one-third of control cases used rescue antiemetics (0 vs. 34%). Conclusion Using the combination of metoclopramide and ondansetron is recommended as the antiemetic regimen for the reduction of PONV after sleeve gastrectomy. This combination is more helpful when implemented alongside ERAS protocols.

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Endometriosis is among the most frequent causes of appendiceal intussusception. However, there are limited data about this condition. Still, clinical manifestations, diagnosis, and treatment are the same in almost all cases due to accidental implantation of endometrial tissue inside the appendiceal wall. Finally, the only choice of treatment is appendectomy. Here we describe a middle-aged woman with vague pelvic pain that underwent a laparoscopic cystectomy, and during surgery, we came across a mass-like appendix. The pathology report declared that some endometrial tissue inside the appendix confirms the diagnosis of appendiceal intussusception due to endometriosis.