Background: A proper sexual functioning and a satisfying intimate relationship is one of the components for a high quality of life (QoL). However, sexuality among the chronically and/or those who suffer from mental illnesses are not a widely researched or discussed topic. The aim of the study is to explore the association among brief psychiatric rating scale (BPRS), QoL, Taiwanese depression questionnaire (TDQ), sexual desire (SD) in people with schizophrenia (PwS).Methods: This study used a cross-sectional design with 277 psychiatric inpatients. A descriptive analysis, difference analysis and logistic regression model were presented to identify relevant variables that may affect the probability of good QoL. Finally, we used structure equation model to explore the association of BPRS, TDQ, SD and QoL. Results: The mean age of the sample was 43.82±8.43 years old. Quality of life has no significant difference in the obesity and gender of PwS, but male PwS had higher scores of SD than female PwS. For participants with smoking, early illness onset age, shorter illness duration there was a significant higher SD. The logistic regression analysis showed BPRS, depression and SD significantly affected the probability of QoL. By SEM, SD would be positivity correlated with mental status and that SD would indirectly influence QoL. Conclusions: Our results showed that the QoL and SD of the PwS are often associated with interaction between psychological and sociological factors. This study also supports the idea of a close relationship between SD, depression and BPRS. Besides, these factors may predict the probability of good life quality for the PwS.

Objective Patients with schizophrenia are living at the border of society and their sexuality is often neglected. The aim of the study is to explore the association among The Brief Psychiatric Rating Scale (BPRS), quality of life (QoL), Taiwanese Depression Questionnaire, and Sexual Desire Inventory in people with schizophrenia (PwS).Methods This study used a cross-sectional design with 277 psychiatric inpatients. A descriptive analysis, difference analysis, and logistic regression model were presented to identify relevant variables that may affect the probability of good QoL.Results The study showed that male PwS had higher scores of standard deviation (SD) than females in PwS. The study also showed that smoking, early illness onset age, and shorter illness duration demonstrated a significantly higher SD. The logistic regression analysis showed that BPRS, depression, and SD significantly affected the probability of QoL. By structural equation model, SD would be positively correlated with mental status and SD would indirectly influence QoL.Conclusion Our results showed psychological and sociological factors interactions may contribute to the QoL and SD for PwS. This study also demonstrated a close relationship between SD, depression, and BPRS. These factors may predict the probability of good life quality for the PwS.