The prevalence of multimedia applications has drastically increased the amount of multimedia data. With the drop of the hardware cost, more and more mobile devices with higher capacities are now used. The widely deployed wireless LAN and broadband wireless networks provide the ubiquitous network access for multimedia applications. Provision of Quality of Service (QoS) is challenging in mobile ad hoc networks because of the dynamic characteristics of mobile networks and the limited resources of the mobile devices. The wireless network is not reliable due to node mobility, multi-access channel and multi-hop communication. In this paper, we provide a survey of QoS provision in mobile multimedia, addressing the technologies at different network layers and cross-layer design. This paper focuses on the QoS techniques over IEEE 802.11e networks. We also provide some thoughts about the challenges and directions for future research.

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Driver mutations propel oncogenesis and occur much less frequently than passenger mutations. The need for automatic and accurate identification of driver mutations has increased dramatically with the exponential growth of mutation data. Current computational solutions to identify driver mutations rely on sequence homology. Here we construct a machine learning-based framework that does not rely on sequence homology or domain knowledge to predict driver missense mutations. A windowing approach to represent the local environment of the sequence around the mutation point as a mutation sample is applied, followed by extraction of three sequence-level features from each sample. After selecting the most significant features, the support vector machine and multimodal fusion strategies are employed to give final predictions. The proposed framework achieves relatively high performance and outperforms current state-of-the-art algorithms. The ease of deploying the proposed framework and the relatively accurate performance make this solution applicable to large-scale mutation data analyses.

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