For many years, drought is severe in the basins and the mountain area of Nandong underground river basin. The author analyzes the reasons of the drought from the hydrogeological characteristics of the basin, climate characteristics, groundwater pollution ,and study indicates that the drought causes is that shallow groundwater and surface water has been seriously polluted, and it is extremely difficult to look for underground karst water. Then the author analyse solutions to solve these problems: building underground dam in Moshigou to develop Nandong underground river; rising underground water level elevation up to 1253m,it can intercept about 306 million m3 underground water. In this way, the author predict that the water shortage problem can be solved fundamentally in these three basins.

Lycium barbarum polysaccharides (LBPs) are the major polysaccharides extracted from L. barbarum, which is used in traditional Chinese medicine (TCM) for treating diseases. Studies have shown that LBPs have important biological activities, such as antioxidation, anti-aging, neuroprotection, immune regulation. LBPs inhibit oxidative stress, improve neurodegeneration and stroke-induced neural injury, increase proliferation and differentiation of neural stem cell, and promote neural regeneration. Here we have reviewed latest advances in the biomedical activities of LBPs and improved methods for the isolation, extraction, and purification of LBPs. Then, new discoveries to decrease oxidative stress and cellular apoptosis, inhibit aging progress, and improve neural repair in neurodegeneration and ischemic brain injury have been discussed in detail through in vitro cell culture and in vivo animal studies. Importantly, the molecular mechanisms of LBPs in playing neuroprotective roles are further explored. Lastly, we discuss the perspective of LBPs as biomedical compounds in TCM and modern medicine and provide the experimental and theoretical evidence to use LBPs for the treatment of aging-related neurological diseases and stroke-induced neural injuries.