No abstract

Supplied: Capsules, each containing Panmycin* Phosphate (tetracycline phosphate complex), equivalent to 250 mg. tetracycline hydrochloride, and 125 mg.Albamycin,* as novobiocin sodium, in bottles of 16 and 100.

The Connecticut Tumor Registry recorded 5,781 women with carcinoma in situ (CIS) and 7,614 with invasive cervical cancer from 1935 to 1973. True incidence rates for invasive disease were calculated. CIS rates indicated newly diagnosed cases, but true CIS incidence is unknown. Starting in 1945-49, the incidence of invasive cervical declined about 20% in Connecticut before CIS screening could have influenced the disease to that extent. Continuing declines in invasive disease rates after 1955 in Connecticut were probably attributable largely to screening. The persistent occurrence of invasive disease in screened populations and the rapid progression of cancer, with early death among some women with apparently localized disease at diagnosis, suggested that a second class of invasive cervical cancer may exist. Cancers in this class may develop and progress rapidly without a practical possibility of detection in the premalignant stage by cytologic methods. Other screening methods, e.g., metabolic, hormonal, immunologic, or virologic, may be required to control this disease.

No abstract

A large-scale data base was derived from the New Haven Connecticut Childhood Lead Poisoning Prevention and Control Program. A subset of 918 children was examined to explore the associations of blood lead levels in these children and four family operational factors. Elevated lead in the children was positively associated with: (a) larger numbers of children under 6 yr in the family; (b) fewer parents at home; (c) fewer parents employed; and (d) lack of day care. Additional environmental, demographic, and socioeconomic factors in childhood lead poisoning and its control are under study.