Olahraga merupakan suatu gaya yang bekerja pada tubuh atau sebagian dari tubuh yang melampui  kemampuan tubuh untuk  mengatasinya. Dari kegiatan olahraga tersebut bisa terjadi cedera, baik karena jatuh, benturan ataupun salah gerak. Cedera olahraga (sport injury) adalah segala macam cedera yang timbul, baik pada waktu latihan maupun pada waktu berolahraga (pertandingan) ataupun sesudah pertandingan. Cedera olahraga biasanya terkena pada bagian tulang, otot, tendo serta ligamentum. Metode RICE merupakan suatu metode penanganan cedera, yang bertujuan untuk mencegah cedera lebih lanjut dan mengurangi rasa nyeri. Tujuan pengabdian kepada masyarakat ini adalah untuk memberikan bekal keilmuan dalam bidang penanganan cedera olahraga dengan metode RICE pada Rukun Krida Muda (RKM) di Desa Guyangan, secara teoretis dan praktis dalam meningkatkan pengetahuan penanganan cedera olaharaga di lapangan. Kegiatan ini dilaksanakan pada hari Minggu 27 September 2020 di desa Guyangan, Nogotirto. Metode yang digunakan dengan sosialisasi dan pelatihan yang disampaikan kepada Rukun Krida Muda (RKM) secara langsung namun tetap menerapkan protokol kesehatan secara tertib. Materi yang disampaikan pada sosialisasi ini adalah tentang penanganan cedera olahraga melalui dengan metode rice dan dilanjutkan pelatihan penanganan, didahului dengan sosialisasi sebelum diadakan pelatihan dan pengisian kuesioner di akhir kegiatan setelah mendapatkan perlakuan berupa sosialisasi. Kegiatan ini diikuti oleh 20 orang.  Hasil Kegiatan pelaksanaan program pengabdian masyarakat ini adalah sebagai berikut: 1) kegiatan sosialisasi penanganan cedera olahrga dengan metode RICE terlaksana dengan baik yang ditunjukan dengan tingkat keaktifan bertanya peserta dan 2) kegiatan pelatihan terlaksana dengan baik, setelah diberikan kuesioner  sebanyak 14 responden (70%) menunjukan kenaikan pemahaman penanganan cedera dan sebanyak 6 responden (30%)  masih belum menunjukan kenaikan pemahaman yang signifikan. Dapat disimpulkan ada perbedaan pengetahuan tentang penanganaan cedera olahraga dengan metode RICE setelah melakukan pelatihan.

Nutrition is an important factor in maintaining bone health, such as calcium, magnesium, phosphorus, protein, and iron. Sea cucumber is one of sea creatures that has plenty of nutrition which is for the body. Objective : To compare the nutrition of Susu sea cucumber, Gosok sea cucumber, Gamat sea cucumber, and packaged milk so they can be used as alternative source in bone health. Methods : The in vitro test using three samples of sea cucumber and three different kinds of packaged milk for kids. The test was performed to five nutritions e.g. calcium, magnesium, phospor, protein, and iron. The analysis results used independent sample test methode and anova test. Results : Sea cucumbers can meet the number of daily nutritional needs. Calcium in sea cucumbers is higher than that of milk (95% CI:-1969.85354-4094.26021). Its phosphorus is higher than that in milk (95% CI:-224.68925). Its magnesium is higher than that in milk (95% CI: 1499.67724-3243.20276). Its protein is higher than that in milk (95% CI: 18.71876-67.70790). Its iron is higher than that in milk (95% CI: 25.08204-54.45796). Conclusion : The nutrition in sea cucumber is greater than that in packaged milk. Susu sea cucumber is better than that in the other two types. Sea cucumber could be used as alternative source for bone health.

Background:  Estrogen deficiency in menopausal women induces bone loss and makes them prone to pathological fractures. Age, body mass index (BMI), parental history of osteoporosis, and smoking tobacco also increase bone loss and pathological fractures. This study aims to determine whether age, BMI, parental history of osteoporosis, and smoking tobacco can predict pathological fractures in menopausal women. Moreover, the relationship between the early detection of osteoporosis with pathological fracture incidence will also be determined. Methods: This is an analytic observational epidemiological research with a cross-sectional retrospective design that involved 40 menopausal women. The data were collected from the patients' medical records 2020 in Obstetrics and Gynecology Clinic, Asri Medical Center (AMC) Muhammadiyah Hospital, Yogyakarta. The predictive factors for pathological fracture (age, BMI, parental history, smoking tobacco) were analyzed by using Fisher's exact test and the relationship between osteoporosis early detection, including bone mineral density (BMD) value, parathyroid hormone (PTH) levels, osteocalcin levels, and osteoporosis self-assessment tool for Asians (OSTA) score, with pathological fractures were investigated by using the chi-square test. Result: Age has a significant relationship with the occurrence of pathological fractures in menopausal women (OR = 6.6, 95% CI: 1.128-8.604, p = 0.042), while BMI, parental history of osteoporosis, and smoking tobacco did not have a significant relationship with pathological fractures (p > 0.05). Early detection of BMD and PTH was also found to have a significant relationship to fracture incidence. Additionally, menopausal women with high PTH levels and osteoporosis BMD values are eight times and four times greater risk of acquiring fractures than menopausal women with normal BMD values and PTH levels. Conclusion: Age can be a predictive factor for pathological fractures, and the early detection of PTH and BMD is related to the occurrence of pathological fractures in menopausal women.

<p><strong>Aim</strong> <br />To determine the effect of secretome hypoxia mesenchymal stem cells (SH-MSCs) on the relative gene expression of hypoxia inducible factor-1a (HIF-1a) and basic fibroblast growth factor (bFGF) in accelerating histomorphometric repair of tendon to bone interface healing in rats acute rotator cuff tear (RCT) model.<br /><strong>Methods <br /></strong>This is experimental research with posttest control group design. Thirty-male Wistar rats were divided into five treatment<br />groups: healthy group and rotator cuff reconstruction group included four groups: SH-MSCs W2 (the treatment group was given a SH-MSCs 0.5 mL and terminated at weeks 2), NaCl W2 (the control vehicle group was assigned NaCl 0.5 mL and terminated at weeks 2), SH-MSCs W8 (the treatment group was given a SHMSCs 0.5 mL and terminated at weeks 8), and NaCl W8 (the control vehicle group was given NaCl 0.5 mL and terminated at weeks 8). All the rats were terminated on day termination and HIF-1a and bFGF gene expression were analysed using qRT-PCR.<br /><strong>Results</strong> <br />SH-MSCs significantly increased the HIF-1a and bFGF gene expression than the NaCl group even in week 2 and week 8.<br />The highest increased gene expression of HIF-1a and bFGF was on week 8.<br /><strong>Conclusion</strong> <br />SH-MSCs are important in the healing repair process of the tendon-to-bone interface in acute RCT model rats through<br />increasing gene expression of HIF-1α and bFGF.</p>