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The physiological derangements during and following the administration of higher oxides of nitrogen have been studied in dogs anaesthetized with pentobarbitone. The dogs were exposed to concentrations of nitric oxide or nitrogen dioxide between 0.1 and 2.0 per cent over periods between 5 and 136 minutes. Despite the inhalation of 98 per cent oxygen, death was always associated with a critical reduction in arterial oxygen content. This was caused by one or more of the following three factors: methaemoglobinaemia, low arterial Po 2 , and acidaemia which caused a shift of the oxyhaemoglobin dissociation curve. The reduction of arterial Po 2 was caused by an outpouring of fluid into the alveoli

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This paper examines some of the ways gifted students are said to be different from non-gifted students by comparing the responses of 475, 9-year-old ''gifted'' students with those of 230 average-attaining 13-year-old students on the same mathematical problem-solving questions. The questions were specifically written for mathematically gifted 9 year olds as part of the World Class Tests project. The performance and approaches used by students in the two samples were found to be very similar, as was the frequency of different responses to the questions, suggesting that many of the mathematically ''gifted'' are not qualitatively different in their problem-solving approaches from students of average ability, but are merely precocious.