Possible predictors of hospitalization for adolescents with conduct disorder seen in psychiatric emergency service Objective: The aim was to investigate predictors of hospitalization of adolescents with conduct disorder (CD) seen in emergency service of a mental health hospital.Method: Patients were evaluated retrospectively by age, gender, school status, family structure, presenting symptoms and their duration, comorbid psychiatric diagnoses, prior emergency service or outpatient clinic use, prior psychiatric hospitalization and family history of any mental disorder, according to first presentation during a 6-month period.Results: Mean age was 15.69±1.26 (12-17) years. Of the total of 144 patients, 61.8% (n=89) were female and 50 (34.7%) were hospitalized. Adolescents admitted to the inpatient unit presented significantly more often with suicidal ideation, had longer symptom duration, and were more likely to have a comorbid psychiatric disorder and a family history of a psychiatric disorder compared to those not admitted. In multivariate logistic regression analysis, suicidal ideation, having a comorbid psychiatric disorder, and having family history of a mental disorder predicted admission to the psychiatric inpatient unit. Conclusion:Clinicians in emergency settings should be aware of the prediction of hospitalization in adolescents with CD who have suicidal ideation, a comorbid psychiatric disorder and family history of a mental disorder. Suicide attempt seems to have an indirect effect, rather than a direct effect, on the prediction of hospitalization in youths with CD.
Amaç:Yüksek manyetik alan yaygın olarak biyolojik dokular için zararsız kabul edilse de, biyolojik etkileri konusunda fikir birliği yoktur. Bu çalışma, basit ve yaygın olarak kabul gören Allium testini kullanarak biyolojik dokulardaki manyetik alanın muhtemel genetik hasarlarını araştırmayı amaçlamaktadır. Gereç ve Yöntemler:Aynı büyüklükte sağlıklı Allium cepa (soğan) bitkileri 0, 8, 24, 72 saat 0,5 Tesla manyetik alana maruz bırakılan dört grupta incelendi. Maruziyet sonrası Allium testi yapılmış ve her grup için en az 4.000 hücre incelenmiştir. Bu hücrelerde gözlemlenen kromozom anormallikleri analiz edildi ve fotoğraflandı.Bulgular: Manyetik alan uygulaması, mitotik aktiviteyi olumsuz etkiledi. Kromozomal sapmalar, manyetik alana maruz kalma sürelerine oranla arttı. En sık görülen sapmalar C-metafaz, yapışkanlık (stickiness), geri kalmış kromozom (lagging chromosome), anafaz köprüsü (anaphase bridge), mikronükleus (micronucleus), düzensiz anafaz (irregular anaphase) ve kutup sapması (polar deviation) oldu. Grup Objective: Although the high magnetic field is commonly accepted as harmless for biological tissues, there is no consensus about its biological effects. This study aims to investigate probable genetic damages of magnetic field on biological tissues using a simple and widely accepted method, Allium test. MaterialsandMethods:The same sized healthy Allium cepa (onion) plants were exposed to 0.5 Tesla magnetic field for 0, 8, 24 and 72 hours as groups of four. Allium test was applied and at least 4.000 cells were counted for each group. Observed chromosomal aberrations were analyzed and photographed.Results: Magnetic field application adversely affected the mitotic activity in the experiment group compared to the control. The chromosomal aberrations increased in proportion to increased magnetic field exposure times. The most encountered aberrations were C-metaphase, stickiness, lagging chromosome, anaphase bridge, micronucleus, irregular anaphase, and polar deviation. The group comparisons showed statistically significant differences between the control group and 8, 24 and 72 hour magnetic field exposure groups. Conclusion:This study has shown potential genotoxic and mutagenic effects of high magnetic field on Allium cepa root tip cells using Allium test. Although there is a need for more studies, the data in the study show that the strong magnetic field leads to chromosomal disorders.
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