Becaplermin gel remains the only US Food and Drug Administration (FDA)-approved growth factor for the treatment of diabetic neuropathic foot ulcers. Becaplermin gel has shown to be efficacious in a number of clinical trials. The FDA has added a black box warning label about the risk of cancer associated with the use of three or more Becaplermin tubes. Other adverse drug reactions associated with Becaplermin gel use are minimal. There is a need for further research regarding the true correlation between cancer and Becaplermin gel use.
While the concepts related to diversity and inclusion are commonly found as part of universities' mission and vision, implementing these concepts into practice can present a challenge. This study identified discrepancies between concepts and practice of diversity and inclusion at a multidisciplinary health sciences university. The results indicated that participants experienced inclusion along a range of engagement. Hispanic/Latino students, faculty, and staff as well as lesbian, gay, bisexual, transgender, and queer students and staff experienced disparaging behavior on a regular basis at the University, which contributed to fear. The results demonstrate barriers to the inclusion efforts and indicate that the university must bridge the gap between diversity concepts and practice.
An isolated medial cuneiform fracture is a rarely encountered injury of the foot. We present a case of an isolated medial cuneiform fracture in a patient after sustaining a fall from a 15-foot height. Treatment consisted of primary arthrodesis of the first tarsometatarsal joint due to a high degree of comminution and intra-articular pain. When radiographs are inconclusive and the index of suspicion remains high for a lesser tarsus fracture, computed tomography is recommended. In patients with minimal displacement, conservative treatment is usually successful in achieving osseous fusion. When the fracture is displaced, intra-articular, or comminuted, surgical intervention, including open reduction with internal fixation and primary arthrodesis, should be considered.
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