Telah dilakukan evaluasi kerasionalan penggunaan obat antirettroval (ARV) pada pasien bayi dan anakpenderita HIV di Rumah Sakit Anak dan Bunda RSAB Harapan Kita Jakarta. Penelitian dilaksanakan denganmetode diskriptif terhadap 37 pasien bayi dan anak yang menderita HIV dalam periode Januari sampai denganDesember 2011. Data dikumpulkan sesuai dengan jenis kelamin, usia, berat, tipe obat, dosis obat, dan frekuensipemberian obat, yang diperoleh dari catatan medis pasien di RSAB Harapan Kita Jakarta. Hasil evaluasimenunjukkan bahwa 21 orang pasien berusia dari 1,5 bulan sampai dengan 13 tahun, dan 16 orang pasien berusiakurang dari 1,5 bulan. Kerasionalan penggunaan tipe-tipe antiretroviral tergantung 100% pada akses terapiantiretroviral. Kerasionalan, ketepatan dan indikasi penggunaan obat antiretroviral 37 orang pasien bayi dan anakyang menderita HIV, terjadi peningkatan rata-rata nilai kadar CD4 sebesar 7,867. p sebesar 0,002 (p < 0,05) yangberarti terdapat perbedaan bermakna nilai kadar CD4 sebelum dan sesudah diberi obat antiretroviral.Kerasionalan penggunaan jenis obat antiretroviral dari ketepatan dosis, kurang dosis 9 kali (15,26%), tepat dosis25 kali (42,37%), dan lebih dosis 25 kali (42,37%). Dan dari frekuensi pemberian obat, sudah tepat 29 kali(49,14%) dan tidak tepat 30 kali (50,86%).
Hypertension is major comorbidity yet difficult to manage in hemodialysis patients. Pharmacist's role to improve the clinical outcome of hypertensive hemodialysis patients needs to be evaluated. The study objective was to evaluate the effect of pharmacist counseling in lowering systolic and diastolic blood pressure in hypertensive hemodialysis patients in hemodialysis unit of Fatmawati Hospital Jakarta in 2018, by controlling some confounders. The study used a quasi-experimental design with pretest-posttest, conducting on age, gender, education, smoking habit, and payment method-matched intervention and control groups. The research sample was taken by consecutive sampling method for 30 patients in the intervention group and 28 patients in the control group. Pharmacist counseling was carried out only in the intervention group. The parameter used were predialysis, intradialysis, and postdialysis systolic and diastolic blood pressure. The results showed that there were significant differences in pretest and posttest (p < 0.05) for predialysis systolic and diastolic blood pressure in the counseling group. In multivariate analysis with backward method, pharmacist counseling was found to be the most determinant factor in reducing predialysis systolic blood pressure (p < 0.05) controlled by education level. It also significantly reduced predialysis diastolic blood pressure controlled by gender, intradialysis systolic blood pressure, and intradialysis diastolic blood pressure controlled by age. In conclusion, pharmacist counseling counseling was the most determinant factor in lowering pre-and intradialysis blood pressure in the hypertensive hemodialysis patient.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.