Introduction. e learning and study strategies of entry-level physical therapist (PT) students may not be as effective as those needed for success in an entry-level PT education program. e Learning and Study Strategies Inventory, third edition (LASSI) is a reliable tool to assess learning and study strategies. e purpose of this study was to assess the learning and study strategies of first-year PT students and if the strategies change over the first year. Review of Literature. ere is little research on using the LASSI with PT students; however, the LASSI has been used with other health care professional students. Subjects. e participants (n = 211) were from 5 cohorts of PT students in their first year of an entry-level PT education program. Methods. In the first week of the curriculum the students took the LASSI in class. e results were released individually to each student. No intervention was provided. At the end of the first year, the students retook the LASSI. Paired samples t-tests were run to determine whether the 10 subtest mean percentile scores changed significantly from baseline to follow-up and how they compared to established LASSI benchmarks.Results. Six subtest scores, Anxiety, Attitude, Concentration, Information Processing, Selecting Main Ideas, and Test Strategies, showed significant changes (P # .005) from baseline to follow-up. However, all subtest averages fell below the 75th percentile mark, which is reported as the threshold requiring reflection to improve skills for learning and study strategies. Discussion and Conclusion. Students, on average, may not have adequate learning and study strategies when they start an entry-level PT education program. e LASSI may be an effective tool to focus resources in a timely and proactive manner for those students who may need them. Determining the resources needed earlier may decrease the need for later remediation, attrition, or licensure examination failures.