Background Leiomyomas are benign smooth muscle tumors that are rarely diagnosed in the nasal cavity and paranasal sinuses. Objective This systematic review summarizes the histopathologic and clinical tumor characteristics, surgical management, and follow-up of sinonasal leiomyomas. Methods A systematic review of the literature on sinonasal leiomyoma was performed by applying the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Studies that met the inclusion criteria were assessed for level of evidence. Patient demographics, clinical and pathological tumor characteristics, primary intervention, and results of follow-up were evaluated. Results Forty studies including 84 patients with sinonasal leiomyoma were identified. The tumor was most often located in the nasal cavity (47/84, 56%) originating from the inferior turbinate (32/84, 38%). Patients mostly presented with symptoms originating from an intranasal mass, including recurrent epistaxis (41/84, 49%), nasal obstruction (43/84, 51.2%), and localized facial or head pain (25/84, 29.8%). Surgery was performed in all cases. An endoscopic approach was most frequently chosen. Recurrence occurred only twice (2.4%). Morbidity was noted in 2 cases (2.4%) following postoperative bleeding and 1 (1.2%) case following a CSF leak. Conclusion Sinonasal leiomyomas are neoplasms of the smooth muscle manifesting clinically with recurrent epistaxis and nasal obstruction. Management goal is total resection with clear margins to avoid local recurrence.
es un instrumento integral de medición de calidad de vida que evalúa los resultados funcionales y estéticos después de la rinoplastia. Objetivo: evaluar los resultados informados por los pacientes después de la cirugía nasal con el uso de dicha escala. Diseño: Estudio observacional descriptivo Metodología: se inscribieron 78 pacientes. Los criterios de inclusión fueron pacientes mayores de 18 años con obstrucción nasal o deformidad estética que se sometieron a una rinoplastia estética y funcionalrealizada por el autor principal desde mayo de 2016 hasta mayo de 2017 en Perth, Australia. Se le pidió a los pacientes incluidos en el estudio que completaran la escala en 5 momentos diferentes: antes de la cirugía, 6 semanas, 3 meses, 6 meses y 1 año después de la cirugía. El análisis se realizó utilizando Stata 14 mediante la evaluación de la confiabilidad test-retest, fiabilidad de consistencia interna; validezde constructo y comparación de los valores pre- y postoperatorios. Resultados: la edad del paciente varió de 18 a 80 años. La edad promedio fue de 33,03 años con una desviación estándar de 11,75 años. El valor mediano preoperatorio fue de 21 con un rango intercuartílico (18-26). Los resultados de RHINO a las 6 semanas estuvieron en la mediana de 44 (40-48), el resultado de la escala a los 3 meses fue de 44 (39-47), el resultado de la mediana a los 6 meses fue de 42 (38,5-46,5) y el resultado de la mediana al año fue de 46 (39-48). En los resultados generales,
Background:
The aim of this study was to determine the advantages of preoperative sentinel lymph node mapping (SLNM) by single photon emission computed tomography/computed tomography (SPECT / CT) in patients with early-stage cutaneous head-and-neck malignancies.
Materials and Methods:
We conduct a 7-year and 6 months retrospective, cross-sectional study. Patients with early-stage malignant head-and-neck skin tumors and cutaneous adnexa who underwent SLNM by SPECT/CT from March 2012 and December 2019, were included in the study.
Results:
We retrospectively analyzed 28 patients: Melanoma was the most frequent tumor (64.2%), followed by squamous cell carcinoma (25%). The anterior cheek was the most common functional subsite (25%). Twenty-seven patients (96.4%) had a successful SLN detection with SPECT/CT. Neck lymph node dissection was performed in 23 patients (82.1%). According to the pathological specimen, lymph nodes were found in all of them; hence, the efficacy of the SPECT/CT for SLNM was 100%. At 7-year follow-up, systemic recurrence was found in one patient (3.6%), another had locoregional recurrence (3.6%), and the mortality rate was 3.6%.
Conclusions:
In early-stage malignant head-and-neck skin tumors, there is a high concordance between SLN found by SPECT/CT and the histopathological results. Preoperative SPECT/CT accurately detects the SLN, assesses unexpected lymph nodes and their drainage pathways, and facilitates their location by reliably showing the relationships between sentinel nodes and important anatomic structures. This allows to perform a clear preoperative evaluation, an accurate staging for all patients and to avoid excessive dissections that could result in cosmetic and functional deformities.
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