This was a single-center retrospective cohort study of women with singleton gestations with cerclage placed between 2016-2021 who were later diagnosed with PPROM. Cerclage removal was defined as immediate if removal was < 24 hours (h) from PPROM and delayed if >24h. Primary outcome was PPROM to delivery interval in days (d) for PPROM < 37 weeks (w). Secondary outcomes were delivery interval for women with PPROM < 34w, latency >48h and >7d, antenatal corticosteroid course to delivery interval < 7d, antibiotic use, tocolytic use, chorioamnionitis and a composite neonatal outcome (admission to NICU, APGAR < 7 at 1 minute, arterial pH < 7.2 and neonatal morbidity or mortality). RESULTS: Of 257 women with cerclage, 60 (23.3%) had PPROM. Cerclage was removed immediately in 29 (48.3%), and in 31 (51.7%) removal was delayed with average delay of 7.2d (1-34). Baseline characteristics, indication for cerclage, gestational age at cerclage placement and PPROM were similar between groups. Interval from PPROM to delivery was significantly higher in the delayed removal group for PPROM < 37w (8.0AE1.4 vs 1.0AE0.4 d, p< 0.001) and PPROM < 34w (8.9AE1.6 vs 1.5AE0.7 d, p< 0.001). Women with a delayed removal were more likely to deliver >48h (58.1% vs 10.3%, p< 0.001) and >7d (45.2% vs 6.9%, p< 0.001) after PPROM. Those with immediate removal were more likely to receive antenatal corticosteroids < 7d from delivery (91.2% vs 31.8%, p¼0.01) and less likely to develop chorioamnionitis (17.2% vs 41.9%, p¼0.03). Composite neonatal outcome was similar between groups. CONCLUSION: Cerclage retention following PPROM may prolong interval to delivery by approximately one week at the expense of increased rates of chorioamnionitis and suboptimal antenatal corticosteroids exposure.

CONCLUSION: Most patients with a malpositioned IUD did not have IUD replacement and abandoned all LARC therapy. These are important preliminary findings regarding LARC abandonment associated with IUD malposition that will help shape further studies as well as clinical counseling.

Introduction:The aim of this study was to describe the sexual and reproductive goals of female adolescents with human immunodeficiency virus (HIV) in an urban cohort and decipher if they vary depending on the mode of HIV acquisition. Methods: We conducted in-depth qualitative interviews with 25 Black and/or Hispanic/Latinx female adolescents living with HIV (14 perinatally, 11 behaviourally acquired) aged 17-25 years who have access to care and antiretroviral therapy at an urban public hospitals (NYC, NY). Interviews were transcribed, coded and analysed using thematic analysis. Results: Interviews demonstrated that access to antiretroviral therapy and HIV disclosure to a sexual partner were critical aspects of sexual health for the majority of participants. Persons with perinatal HIV defined motherhood as a source of self-validation and were confident that antiretroviral therapy prevents HIV transmission. Persons with behaviourally acquired HIV viewed their status as an insurmountable barrier that will prevent them from attaining sexual intimacy with a partner and expressed persistent concerns about HIV transmission during pregnancy despite reassurance from medical providers. Conclusion: Sexual and reproductive perspectives of adolescents/young women living with HIV are multifactorial, highly stigmatized, and likely influenced by the mode of HIV acquisition. This population may benefit from patient-centred care models, including sexual health counselling that addresses sexual agency, intimacy, parenting and transmission risk reduction.