In the current study, a novel electrode was prepared by utilizing electropolymerization as well as immobilization technique for the resolution of antibacterial drug Ciprofloxacin (CFX). Cyclic voltammetric (CV) technique was adopted to explore the properties of poly(Evans blue) sodium dodecyl sulphate doubly modified carbon paste electrode (PEBSDSMCPE). A significant enhancement in the electrochemical activity was observed at modified electrode compared to bare carbon paste electrode (BCPE). The effect of variation in sweep rate was also performed to evaluate the total number of electrons transferred during the oxidation of CFX. The mass transfer process taking place at the electrode surface was also examined and it was found to be controlled by diffusion phenomena. Under optimized circumstances the limit of detection (LOD) and quantification limit (LOQ) were achieved to be 1.83×10−7 M and 6.11×10−7 M respectively. PEBSDSMCPE was successfully utilized for the selective determination of CFX, Riboflavin (RFL) and Estriol (EST). The current proposed method was well adopted for the analysis of real sample.

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The poly (gabapentin) film was prepared on the surface of carbon paste electrode by electrochemical method using cyclic voltammetric technique. The poly (gabapentin) film-modified carbon paste electrode was calibrated with standard potassium ferrocyanide solution in 1 M KCl as a supporting electrolyte. The prepared poly (gabapentin) film-coated electrode exhibits excellent electrocatalytic activity towards the detection of dopamine at physiological pH. The scan rate effect was found to be diffusion-controlled electrode process. The concentration effect of dopamine was studied, and the redox peak potentials of dopamine were dependant on pH.

The crystal structure of ethiprole {systematic name: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethanesulfinyl-1H-imidazole-3-carbonitrile}, C13H9Cl2F3N4OS, a phenylpyrazole-based insecticide, is presented. The pyrazole ring carries four substituents: an N-bound 2,6-dichloro-4-trifluoromethylphenyl ring and C-bound amine, ethanesulfinyl, and cyano groups. The sulfur atom of the ethanesulfinyl group is trigonal–pyramidal and stereogenic. The structure exhibits whole-molecule configurational disorder due to superposition of enantiomers. The crystal packing is dominated by strong N—H...O and N—H...N hydrogen bonds, which form R 4 4(18) and R 2 2(12) ring motifs. Since the ethiprole molecule is quite small, and structure solution and refinement were straightforward, the structure presents a convenient instructional example for modelling whole-body disorder of a non-rigid molecule. To this end, a step-by-step overview of the model-building and refinement process is also given. The structure could form the basis of a useful classroom, practical, or workshop-style example.

The structure of the title compound, C15H8N4Cl2F6OS, a phenylpyrazole-based insecticide related to ethiprole, fipronil, and derivatives thereof is presented. The pyrazole ring has four chemically diverse substituents, namely a nitrogen-bound 2,6-dichloro-4-trifluoromethylphenyl and carbon-bound cyano, ethylsulfanyl, and 2,2,2-trifluoroacetamide groups. The pyrazole and phenyl rings are perpendicular, subtending a dihedral angle of 89.80 (5)°. In the crystal, strong N—H...O hydrogen bonds link the molecules into chains that extend parallel to the a-axis.