These lines of evidence suggest that sulforaphane can suppress the cancer stemness and tumor-initiating properties in OSCC-CSCs both in vitro and in vivo.

With growing attention being devoted to autonomous vehicle (AV) safety, people have recently attached importance to high-definition (HD) maps. HD maps are not limited by environmental factors and can limit AVs driving in certain lanes. HD maps provide accurate auxiliary information on factors such as road geometry, traffic sign placement, and traffic topology. Nowadays, most HD maps are made from point clouds data, and this data contains accurate 3D position information. However, the production costs associated with HD maps are substantial. This article proposes an algorithm that reduces a great amount of time and human resource. The algorithm is divided into three phases, lane lines’ extraction from point clouds, modelling lane lines with attributes, and building OpenDRIVE file. The algorithm extracts lane lines resting on intensity value within the range of roads. Next, it models lane lines by cubic spline interpolation with the result of first phase, and build the OpenDRIVE file following the announcement of OpenDRIVE. The final result is compared with the verified HD map from the mapping company to analyze the accuracy. The root mean square (RMSE) obtained were 0.069 and 0.079 m for 2D and 3D maps, respectively.

To achieve higher automation level of vehicles defined by the Society of Automotive Engineers, safety is a key requirement affecting navigation accuracy. We apply Light Detection and Ranging (LiDAR) as a main auxiliary sensor and propose LiDAR-based Simultaneously Localization and Mapping (SLAM) approach for Positioning, Navigation, and Timing. Furthermore, point cloud registration is handled with 3D Normal Distribution Transform (NDT) method. The initial guess of the LiDAR pose for LiDAR-based SLAM comes from two sources: one is the differential Global Navigation Satellite System (GNSS) solution; the other is Inertial Navigation System (INS) and GNSS integrated solution, generated with Extended Kalman Filter and motion constraints added, including Zero Velocity Update and Non-Holonomic Constraint. The experiment compares two initial guesses for scan matching in terms navigation accuracy. To emphasize the importance of a multi-sensor scheme in contrast to the conventional navigation method using the stand-alone system, the tests are conducted in both open sky area and GNSS signal block area, the latter might cause Multipath and Non-Line-Of-Sight effects. To enhance the navigation accuracy, the Fault Detection and Exclusion (FDE) mechanism is applied to correct the navigation outcome. The results show that the application of NDT and FDE for INS/GNSS integrated system can not only reach where-in-lane level navigation accuracy (0.5 m), but also enable constructing the dynamic map.

No abstract

No abstract