Say-Barber-Biesecker-Young-Simpson's syndrome is one of the Ohdo-like syndromes. It is a very rare congenital condition that is commonly defined by its main clinical features that are blepharophimosis, ptosis, mental retardation, and delayed motor development. They are often associated with skeletal manifestations that are joint laxity, long thumbs and toes, and hypoplastic and/or dislocated patellae. To our knowledge, the available literature does not report any case where attention is drawn to management of skeletal aspect of this specific syndrome, especially surgically. We report 2 cases of SBBYS syndrome with patellar dislocation that we followed for 11 years. One case (with bilateral dislocation) was managed conservatively, and the other (with unilateral dislocation) underwent conservative and surgical treatment. Both had good functional outcome at follow-up. This experience shows that patellar abnormality in this condition can be efficiently addressed conservatively and/or surgically with satisfying results.
Heterotopic ossification (HO) designates a bone tissue formation within an atypical anatomical location and is commonly diagnosed in patients whom have suffered major traumas. The following case report presents a non-traumatic source of HO. A causality is deduced between the HO formation and an important inflammatory reaction originating from a Coronavirus infection. In contrast to other studies not only is the source non traumatic but the HO formation is unilateral. In systemic inflammatory reactions vigilance towards HO should be enhanced especially in patients treated during prolonged periods of time in intensive care units (ICU).
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