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Background: Pakistan is ranked at 6th place amongst the top 10 countries of the world. The number of estimated cases with diabetes in our country are 5.2 million in 2000 and projected to be 13.9 million in 2003. The objective of this research to examined risk for 2 diabetes and conditioned on directly ascertained parental diabetes status among population of Karachi, Pakistan.

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Background: Type 2 diabetes mellitus has become a universal problem. Globally 80% of lower and middle income countries are suffering from diabetes. Different studies show that offspring from diabetic parents growth indicators were disturbed the lipid profile and growth indicators. The objective of the study was to determine the levels of lipid profile and growth indicators among offspring of diabetic parents. Material and methods: Cross sectional study was done. Total 180 subjects were recruited from Dow university of Health sciences and classified as both parents were diabetic (BDP), Single Parents Diabetic (SDP) and no parents were diabetic (NDP). The Growth indicators lipid profile was measured. The analyst concentration of Lipids was analyzed by The Roche Hitachi Analyzer 902 Automated Analyzer automatically .Fasting blood sugar levels was determined by glucose oxidase. Results: Those offspring who gave history of diabetes in parents had their growth indicators and Lipid Profile were disturbed or raised when compared with non-diabetic parents. 25.6%, 5.6% and 5.6% of offspring belongs to Both Parents Diabetic (BDP), Single Diabetic Parents (SDP) and Not Diabetic Parents (NDP) respectively have obese. Similar lipid profile indicators also raised as More BDP and SDP subjects had high cholesterol (>200 mg/dL) than NDP (76.9% and 29.6% versus 10% respectively), More BDP and SDP subjects had high cholesterol (>150 mg/ dL) than NDP (23.1% and 2.8% versus 0% respectively). More BDP and SDP subjects had high cholesterol (>130 mg/dL) than NDP (76.9% and 29.6% versus 15% respectively). Conclusions: Lipid profiles of offspring were related to diabetic parent's history. Early screening and change in lifestyle modification can be a preventive intervention for the risk of developing diabetes in future. Methodology Study area, design and period, sampling technique, sample size Participants were inducted from different campuses of Dow

ABSTRACT… Objectives:To have a look on the effect of sea life by checking blood pressure and testing blood fasting sugar, total cholesterol, HDL and triglycerides of the sea farers deployed on different positions at ship. Study design: This was a cross sectional descriptive and clinical study. Setting: Port Health Department, Kemari, Karachi. Period: 1 st October 2016 to 22 April 2017. Methods: Random sampling was done and a total 62 personnel from different branches of ships were selected. The study subjects aged ≥ 25 belonging to different shipping companies were called at Port health dispensary for collection of blood sample and checking of blood pressure. Height and weight measurement was done and also smoking history was revealed. Blood Tests, fasting sugar, HDL, Cholesterol, and Triglycerides were performed. Results: Overall the age range was 25 -55 years and a mean of +/-SD of 38.95 +/-8.57. Maximum population was of the age group 36 -45 years. Hypertension both systolic and diastolic in all seafarer (100%) was the main findings. HDL and Triglycerides were also found grossly raised. Age, height, weight, and smoking history data showed non-significant (P>0.05) results. Also, Professional categories and laboratory findings results were not found significant P >0.05. Conclusion: Seafaring is one of the hard profession which terribly affect the health of sea farers. Preventive measures at primary and secondary level to be organized and implemented.