Introduction and Importance: Sacral chordoma is a rare tumor arising from notochord remnants. Sacral pain is the most common sign. The authors report the case of a sacral chordoma diagnosed in a urology department. It was a rare cause of erectile dysfunction and it was unusually revealed by lower urinary tract symptoms (LUTSs). Case Presentation: A 67-year-old man had severe dysuria associated with erectile dysfunction. On digital rectal examination, we palpated a mass protruding through the posterior wall of the rectum. The gluteal region is infiltrated by a firm mass. MRI revealed an osteolytic sacral tumor. A percutaneous biopsy of the tumor was performed. A pathological examination confirmed the diagnosis of sacral chordoma. The patient had palliative radiotherapy. One year after radiotherapy, he had rectal stenosis associated with severe constipation. Clinical Discussion: Sacral chordoma is a rare malignant tumor. Sacralgia is the most common sign. LUTS and erectile dysfunction were rarely reported in patients affected by this bone tumor. MRI is very suggestive of this pathology. Diagnostic confirmation requires pathological examination. The curative management consists of a large resection of the tumor. For inextricable tumors, palliative radiotherapy can be carried out. The prognosis of sacral chordoma is defined by a high recurrence potential and a low metastatic risk. Conclusions: Sacral chordoma is a rare bone tumor. It is an unusual cause for LUTS and erectile dysfunction. Complete tumor excision is the only curative treatment. Recurrence after treatment is the main challenge for surgeons.

Introduction and importance: Sacral chordoma is a rare tumor arising from notochord remnants. Scaral pain is the most common sign. We report the case of a sacral chordoma diagnosed in a urology department. It was a rare cause of erectile dysfunction and it was unusually reaveled by lower urinary tract symptoms (LUTS). Case presentation: A 67-year-old man had severe dysuria associated with erectile dysfunction. On digital rectal examination, we palpated a mass protruding through the posterior wall of the rectum. The gluteal region is infiltrated by a firm mass. Magnetic resonance imaging (MRI) revealed an osteolytic sacral tumor. A percutaneous biopsy of the tumor was performed. Pathological examination confirmed the diagnosis of chordoma. Patient had palliative radiotherapy. One year after radiotherapy, he had rectal stenosis associated with severe constipation. Clinical Discussion: Sacral chordoma is a rare malignant tumor. Sacralgia is the most common sign. LUTS and erectile dysfunction were rarely reported in patients affected by this bon tumor. MRI is very suggestive of this pathology. Diagnostic confirmation requires pathological examination. The curative management consists in a large resection of the tumor. For inextricable tumor, palliative radiotherapy can be carried out. The prognosis of chordoma is defined by a high recurrence potential and a low metastatic risk. Conclusions: Sacral chordoma is a rare bon tumor. It is an unusual cause for LUTS and erectile dysfunction. Complete tumor excision is the only curative treatment. Recurrence after treatment is the main challenge for surgeons.

An optimization procedure for multistep temperature-programmed capillary gas chromatography was developed for the analysis of basil essential oil. The current study was planned after performing the following three steps: a preliminary chromatographic study, primary parameter screening, and final method optimization by using 23 factorial and Doehlert designs (DOE). The optimized conditions were obtained by using a split ratio of 1 / 2 , a gas flow rate of 1.3 mL/min, and a heating rate of 2°C/min. This set of conditions was later used for the optimization of the final method. The optimal experimental conditions were subsequently obtained by response surface optimization (isotherm duration = 6.2 min and slope = 1.06°C/min). The compositions of essential oils from six varieties of basil (Ocimum B. (1), Ocimum B. purpurescens opal (2), Ocimum B. minimum (3), Ocimum. B. cinnamon (4), Ocimum B. (marcellas) (5), and Ocimum B. Citriodora (6)) grown in four regions of Algeria (Ouargla, south of Algeria (O); Mostaganem, west of Algeria (M); Algiers, north of Algeria (A), and Constantine, east of Algeria (C)) were determined. A statistical study was performed based on hierarchical ascending classification and principal component analysis to elucidate the relationships between the basil varieties, their region of growth, and their essential oil composition. In addition to identifying several chemotypes, such as linalool, linalool/eugenol, linalool acetate, methyl eugenol, methyl chavicol, eugenol, methyl cinnamate E, and geraniol, a new compound, namely, octadecenamide (Z) (oleamide), was detected in the essential oil of Ocimum basilicum L. from Algiers (A1).