No abstract

Introduction: Assessment of exercise capacity is important for information about lung function and prognosis in primary ciliary dyskinesia (PCD). In addition, deterioration in the pulmonary system may affect cough efficiency, posture, and thoracoabdominal mobility. In turn, this deterioration may also disturb the psychological function of patients with PCD. Therefore, this study aimed to compare exercise capacity, cough strength, thoracoabdominal mobility, posture, and depression in children with PCD and healthy peers.Methods: Twenty-seven patients with PCD and 28 healthy peers were included.Aerobic exercise capacity (3-min step test), cough strength (peak expiratory flow meter), thoracoabdominal mobility (upper chest, lower chest, and abdomen), posture (Corbin postural assessment scale), and depression (Children's Depression Inventory) were evaluated.Results: Patients' number of steps completed, cough strength, and thoracoabdominal mobility were significantly decreased; total posture and depression scores were higher compared with healthy controls (p< 0.05). There was a significant relationship between cough strength and maximal expiratory strength (r = 0.541, p= 0.004) and total number of steps (r = 0.509, p= 0.007) in the patients. Conclusion: Aerobic exercise capacity, cough strength, and thoracoabdominal mobility were impaired, posture was deteriorated, and depression perception elevated in children with PCD compared to healthy peers. Furthermore, aerobic exercise capacity and maximal expiratory strength are related to cough strength in these patients. Rehabilitation programs including aerobic and resistive exercise training, deep breathing and postural exercise, and nutrition counseling may improve these results and better be investigated. Trial registration: Clinicaltrials.gov: NCT03370029; December 12, 2017.

Purpose: The COVID-19 pandemic period may affect the physical and mental health of non-cystic fibrosis (CF) bronchiectasis patients who had lung diseases. In this study, we purposed to compare COVID-19 phobia, quality of life, health anxiety, physical activity level and sleep quality during the pandemic between patients with non-CF bronchiectasis and healthy controls. Methods: Thirty patients and 44 healthy controls were included. COVID-19 phobia (Coronavirus 19 Phobia Scale (CP19-S)), quality of life (Nottingham Health Profile (NHP)), health anxiety (Health Anxiety Inventory (HAI)), physical activity level (short form of the International Physical Activity Questionnaire (IPAQ-SF)) and sleep quality (Pittsburgh Sleep Quality Index (PSQI)) were evaluated. Results: NHP energy, pain and physical mobility scores and moderate-intensity physical activity levels were significantly lower; PSQI sleep disturbance score was significantly higher in patients compared with controls (p0.05). Most of the patients and controls did not perform the recommended moderate or vigorous-intensity physical activity per week. Conclusion: During COVID-19 pandemic, non-CF bronchiectasis patients have deteriorated quality of life, decreased moderate-intensity physical activity and increased sleep disturbance. Both patients and healthy individuals had coronaphobia and low physical activity levels. Therefore, physical activity counselling is important during the pandemic period.

Amaç: Bu çalışmanın amacı evre 3 kronik böbrek hastalığı olan bireylerde solunum kas kuvveti, egzersiz kapasitesi ve fizyolojik harcama indeksini değerlendirmekti. Yöntem: Yirmi dört evre 3 kronik böbrek hastası (46,21±9,48 yıl, 13 kadın (%54,2), 11 erkek (%45,8)) retrospektif olarak incelendi. Solunum kas kuvveti (maksimal inspiratuar basınç ve ekspiratuar basınç) ağız basıncı ölçüm cihazı, egzersiz kapasitesi 6 dakika yürüme testi ve enerji harcaması fizyolojik harcama indeksi ile değerlendirildi. Bulgular: Kronik böbrek hastalarının % 62,5’inde inspiratuar kas zayıflığı (81,29±17,74 cmH2O), % 79,17’sinde egzersiz kapasitesinde azalma (501,92±58,50 metre) ve % 75’inde artmış fizyolojik harcama indeksi (0,47±0,13 atım/metre) vardı. Sonuç: Hastalığın erken evrelerinde olmalarına rağmen evre 3 kronik böbrek hastalarının solunum kas kuvveti ve egzersiz kapasitesinin azaldığı, enerji harcamasının ise arttığı görülmüştür. Bu hastalarda solunum kas ve aerobik egzersiz eğitimi ile solunum kas kuvveti, egzersiz kapasitesi ve enerji harcamasında gelişme sağlanabilir.