Potassium losartan is an example of AT1 receptors antagonist, and it is used for hypertension treatment. Potassium losartanoften is prepared at compounding pharmacies. Thus, the aim of this work is to analyze the dosage forms of potassium Losartan prepared by compounding pharmacies at Montes Claros, MG. Capsules containing 50 mg losartan were purchased commercially in three randomly chosen compounding pharmacies. The average weight of the capsules ranged from 0.136 g to 0.147 g for the same prescription of 50 mg. The test for disintegration of the capsule as described in the methodology above, lies within the parameters established in the Brazilian Pharmacopoeia. It is not conclusive analysis of the mean weight of the capsules, while the disintegration test demonstrated a good quality capsules analyzed.Keywords: potassium losartan; compounding pharmacy; Quality Control RESUMO Losartana Potássica é um exemplo clássico de antagonistas dos receptores da AT1 ativos por via oral,e é utilizada no tratamento da Hipertensão Arterial Sistêmica. A fórmula manipulada em farmácias magistrais deve conter a quantidade de fármaco exata em todas as preparações farmacêuticas. Assim, o objetivo desse estudo foi analisar cápsulas de Losartana Potássica manipuladas em farmácias de Montes Claros, MG. As amostras de Losartana Potássica 50 mg foram adquiridas comercialmente em três farmácias de manipulação escolhidas aleatoriamente. Para a determinação do peso médio e tempo de desintegração da cápsula, foi seguida a Farmacopeia Brasileira. O peso das cápsulas variou de 0,136 g a 0,147 g para a mesma prescrição de 50 mg. O teste para desintegração da cápsula conforme descrito na Farmacopeia se encontrou dentro dos parâmetros estabelecidos.
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