Results of the present study demonstrated that metabolic syndrome, diabetes and gallstone size were associated with CGD. Further prospective studies are needed to understand the clinical importance of this association.

An extensive rescue excavation has been conducted in the ancient harbor of İstanbul (Yenikapı) by the Sea of Marmara, revealing a depositional sequence displaying clear evidence of transgression and coastal progradation during the Holocene. The basal layer of this sequence lies at 6 m below the present sea level and contains remains of a Neolithic settlement known to have been present in the area, indicating that the sea level at ~ 8–9 cal ka BP was lower than 6 m below present. Sea level advanced to its maximum at ~ 6.8–7 cal ka BP, drowning Lykos Stream and forming an inlet at its mouth. After ~ 3 cal ka BP, coastal progradation became evident. Subsequent construction of the Byzantine Harbor (Theodosius; 4th century AD) created a restricted small basin and accumulation of fine-grained sediments. The sedimentation rate was increased due to coastal progradation and anthropogenic factors during the deposition of coarse-grained sediments at the upper parts of the sequence (7th–9th centuries AD). The harbor was probably abandoned after the 11th century AD by filling up with Lykos Stream detritus and continued seaward migration of the coastline.

Neutrophil/lymphocyte and platelet/lymphocyte ratios are predictors for malignant ovarian tumors but not borderline tumors even in case of microinvasion.

Tamoxifen (TAM) is widely used in the treatment of breast cancer, and its paradoxical effects on female genital system are well known. During the past 10 years, many descriptions of nonepithelial uterine malignancies related to long-term TAM usage have been reported in the literature. Four uterine sarcoma patients who had history of TAM usage for previous breast cancer are presented in this study. The mean time of exposure to TAM was 6 (range 3-11) years, and the mean cumulative dose of drug was 43.82 g. All patients were postmenopausal, and the mean age was 66 (range 61-73) years at the time of the diagnosis of the uterine malignancy. Two (50%) patients had uterine malignant mixed müllerian tumor, and two (50%) had leiomyosarcoma. In one (25%) patient was diagnosed with endometrial biopsy made for a postmenopausal vaginal bleeding; the others (75%) were asymptomatic and their diseases were diagnosed during the pelvic examination and transvaginal ultrasonography. All patients underwent surgery +/- adjuvant therapy (chemotherapy and/or radiation therapy), and two (50%) patients died because of the sarcoma. In consequence, early detection of TAM-related uterine sarcoma is required for orderly gynecological examination in patients having history of TAM usage for previous breast cancer.

The Bakri balloon may be performed as a first line of treatment for PPH resistant to uterotonic agents, and can be used not only in tertiary centers but also in limited-resource centers. The inflation volume of the Bakri balloon should be adjusted according to the type of PPH; a volume exceeding 500 mL may be necessary in uterine atony.