Purpose: To assess the efficacy of uterine artery embolization in reducing the uterine fibroid size according to its location. Materials and methods:A retrospective record-based study was conducted at interventional radiology department of prince sultan military medical city in Riyadh city. Medical files of all women above 18 years who underwent uterine artery embolization during the period from January 2015 to January 2020 were reviewed. All included women files were initially assessed for their data including age, puncture site, pre-and post-procedure size and location of the fibroids. Post-procedure size change and complications were assessed.Results: A total of 160 female who underwent uterine artery embolization records for symptomatic fibroid were reviewed and data extracted. Females ages ranged from 18 to 60 years. Fibroid size reduction of less than 50% of its initial size was detected among 38 (44.7%) cases while it was reduced by 50 to 75% of its initial size among 27 (31.8%) cases but 20 (23.5%) cases showed reduction in size exceeding 75% of its initial size. Conclusions:In conclusion, the study revealed that Uterine artery embolization is an effective less invasive, and safe therapy. The procedure efficacy was more among young females with initially small fibroid masses and the highest reduction (> 50%) in fibroid size was detected among females with fibroid at cervix (71.4%), fundus (70%) and lowest was for females with multiple fibroid (50%) with no statically significance (P = 0.432).